SynthesisFrontiers in microbiology2026
Global research status and development trends of chronic obstructive pulmonary disease and gut microbiota: a comprehensive analysis based on bibliometrics and knowledge visualization.
Synthesis in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic obstructive pulmonary disease (COPD) is a common chronic disease characterized by airflow obstruction due to chronic bronchitis and/or emphysema, which can further progress to cor pulmonale and respiratory failure. In recent years, the association between gut microbiota and COPD has attracted extensive attention from researchers. This study aimed to explore the current research hotspots, knowledge gaps, and future research trends in the field of gut microbiota and COPD. Methods: A comprehensive search of literature related to gut microbiota and COPD published between 2009 and 2025 was conducted using the Web of Science and Scopus databases. Bibliometric analyses were performed using VOSviewer, CiteSpace, and R software. Results: The number of publications in this field showed a significant growth trend from 2009 to 2025, with the highest number of publications recorded in 2024. China and the United States were the leading contributing countries, and institutions such as the University of Technology Sydney made important contributions. Conclusion: To our knowledge, this study presents the first quantitative bibliometric analysis of the field of gut microbiota and COPD. The core research hotspots identified include the characteristics of gut microbiota alterations in COPD patients, as well as the reciprocal interactions and underlying mechanisms between COPD and gut microbiota; microbiota intervention strategies have also emerged as an emerging research direction. Investigating immune regulation mediated by gut microbial metabolites has become an important trend in this field. This study provides a comprehensive analysis of the current research status and key hotspots in the field of gut microbiota and COPD, offering important references and insights for subsequent studies in related fields.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.