Evidence map›Paper›PMID 42317779›Full record

ArticleOphthalmology science2026

Intraoperative Anti-VEGF vs. Photocoagulation during Vitrectomy for Branch Retinal Vein Occlusion with Vitreous Hemorrhage: A Randomized Clinical Trial.

Wei Lin, Chuying Deng, Zhong Lin, Qintuo Pan, Yongping Tang, Hao Chen, Xiaoyan Lin, Yong Wei

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ophthalmology science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei LinNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Chuying DengNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Zhong LinNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Qintuo PanNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Yongping TangNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Hao ChenNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Xiaoyan LinNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Yong WeiNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To compare the effects of vitrectomy combined with intraoperative anti-VEGF therapy versus intraoperative sectoral retinal photocoagulation on the anatomical and functional outcomes of branch retinal vein occlusion (BRVO) complicated by vitreous hemorrhage (VH). Design: Randomized, parallel-group clinical trial. Participants: The study included 34 patients diagnosed with BRVO complicated by VH. Methods: Patients were randomly assigned to receive either intraoperative intravitreal injection of 0.5 mg ranibizumab (anti-VEGF group) or sectoral retinal photocoagulation (laser group) after vitrectomy. Postoperative assessments included best-corrected visual acuity (BCVA), visual field, and fluorescent angiography. Main Outcome Measures: Mean deviation (MD) of the visual field at 12 months and intergroup differences. Results: The average MD of the visual field in the anti-VEGF group was significantly lower than that in the laser group (-8.5 ± 4.6 dB vs. -15.1 ± 3.5 dB, Conclusions: Intraoperative anti-VEGF therapy is a safe and effective alternative to sector retinal laser photocoagulation for patients with BRVO complicated by VH undergoing vitrectomy. This approach offers the advantage of preserving the visual field and avoiding CV damage associated with laser treatment. Financial Disclosures: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

Indexed as

Antivascular endothelial growth factorBranch retinal vein occlusionMean deviationVitrectomyVitreous hemorrhage

Identifiers

PMID42317779
PMCPMC13273700

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.