Evidence mapPaperPMID 42317823Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2026

Multimodal Training to Unimodal Deployment: Leveraging Unstructured Data During Training to Optimize Structured Data Only Deployment.

Zigui Wang, Minghui Sun, Jiang Shu, Matthew M Engelhard, Lauren Franz, Benjamin A Goldstein

Abstract read
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zigui WangDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA.
Minghui SunDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA.
Jiang ShuDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA.
Matthew M EngelhardDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA.
Lauren FranzDuke Center for Autism and Brain Development, Duke University School of Medicine, Durham, NC, USA.
Benjamin A GoldsteinDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA.

Funding

Advancing Identification of Late-Talking Children and Mapping their Developmental Trajectories Using Real World Data from Electronic Health RecordsR21DC022440 · NIDCD · DUKE UNIVERSITY · PI FRANZ, LAUREN, GOLDSTEIN, BENJAMIN ALAN · 2024 to 2024
$443k
NIDCD NIH HHS R21 DC022440
6 · The paper itself

Abstract

Unstructured Electronic Health Record (EHR) data-such as clinical notes-contain clinical contextual observations that are not directly reflected in structured data fields. This additional information can substantially improve model learning. However, due to their unstructured nature, these data are often unavailable or impractical to use when deploying a model. We introduce a multimodal learning framework that leverages unstructured EHR data during training while producing a model that can be deployed using only structured EHR data. Using a cohort of 3,466 children evaluated for late talking, we generated note embeddings with BioClinicalBERT and encoded structured embeddings from demographics and medical codes. A note-based teacher model and a structured-only student model were jointly trained using contrastive learning and contrastive knowledge distillation loss, producing a strong classifier (AUROC = 0.985). Our proposed model reached AUROC of 0.705-outperforming the structured-only baseline of 0.656. These results demonstrate that incorporating unstructured data during training enhances the model's capacity to identify task-relevant information within structured EHR data, enabling a deployable structured- only phenotype model.

Identifiers

PMID42317823
PMCPMC13274334

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.