ArticleFrontiers in insect science2026
Regulation of
Article in Frontiers in insect science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Methods: In controlled laboratory cage experiments, newly emerged worker bees were experimentally infected with Results: BP treatment significantly improved survival probability and reduced pathogen load compared to infected controls. During the early infection stage (5 dpi), BP treatment was associated with extensive downregulation of parasite genes, including components of the V-type ATPase pathway. Gene Ontology and KEGG analysis suggested suppression of metabolic and ion transport processes. To further evaluate the potential role of V-type ATPase, RNAi-mediated knockdown resulted in reduced gene expression and showed a trend toward decreased pathogen load and modest improvement in host survival. Discussion: Although the RNAi results do not provide definitive evidence of causality, they support a potential involvement of the V-type ATPase in parasite proliferation. Overall, BP altered the transcriptomic profile of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.