Evidence map›Paper›PMID 42318399›Full record

ArticleFrontiers in medicine2026

The association between the Acute Physiology Score and sepsis in ICU non-surviving patients with inflammatory bowel disease: a retrospective cohort study from the eICU-CRD.

Chenyang Li, Zhexuan Liu, Daniel D Zhang, Fenghua Li, Dong Wang, Yuxin Luo, Yue Yao, Qian Liu, Xu Teng, Shuang Chen and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chenyang Li *Department of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Zhexuan Liu *Department of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Daniel D ZhangDepartment of Biology, University of California Riverside, Riverside, CA, United States.
Fenghua LiDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Dong WangDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Yuxin LuoDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Yue YaoDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Qian LiuDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Xu TengDepartment of Physiology, Hebei Medical University, Shijiazhuang, China.
Shuang ChenDepartment of Pediatric Immunology and Infectious Disease Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, United States.
Xiaolan ZhangDepartment of Gastroenterology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sepsis significantly contributes to ICU mortality in inflammatory bowel disease (IBD) patients. Early risk stratification remains challenging. Methods: This retrospective cohort study utilized the eICU-CRD database, analyzing 190 adult IBD patients who died during ICU admission. We employed weighted logistic regression, restricted cubic splines, and XGBoost to evaluate the association between Acute Physiology Score (APS) and sepsis. Results: Among 190 non-survivors (55 with sepsis), the sepsis group demonstrated significantly higher APS scores (49.71 ± 23.25 vs. 40.66 ± 18.78, Conclusion: APS independently associated with sepsis in ICU non-surviving IBD patients. Given the small sample and study design, these findings are hypothesis-generating and restricted to this subgroup.

Indexed as

Acute Physiology Scoreinflammatory bowel diseaseintensive care unitrisk factorssepsis

Identifiers

PMID42318399
PMCPMC13271910

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.