Evidence map›Paper›PMID 42318644›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Wearable-Derived Diurnal Alignment Between Physical Activity and Device Temperature Predicts Future Disease and Mortality Risk.

Han Chen, Jiahe Wei, Jonathan Cedernaes, Christian Benedict, Athanasios Tsanas, Zhi Cao, Xiao Tan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Han ChenDepartment of Psychiatry, Sir Run Run Shaw Hospital, Zhejiang Key Laboratory of Clinical and Basic Research for Psychiatric Diseases, and School of Public Health, Zhejiang University School of Medicine, Hangzhou, China.ORCID https://orcid.org/0009-0002-0206-7084
Jiahe WeiDepartment of Psychiatry, Sir Run Run Shaw Hospital, Zhejiang Key Laboratory of Clinical and Basic Research for Psychiatric Diseases, and School of Public Health, Zhejiang University School of Medicine, Hangzhou, China.
Jonathan CedernaesDepartment of Medical Sciences, Uppsala University, Uppsala, Sweden.ORCID https://orcid.org/0000-0002-9052-8372
Christian BenedictDepartment of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.ORCID https://orcid.org/0000-0002-8911-4068
Athanasios TsanasUsher Institute, University of Edinburgh, Edinburgh, Scotland, UK.ORCID https://orcid.org/0000-0002-0994-8100
Zhi CaoDepartment of Psychiatry, Sir Run Run Shaw Hospital, Zhejiang Key Laboratory of Clinical and Basic Research for Psychiatric Diseases, and School of Public Health, Zhejiang University School of Medicine, Hangzhou, China.ORCID https://orcid.org/0000-0003-1522-734X
Xiao TanDepartment of Psychiatry, Sir Run Run Shaw Hospital, Zhejiang Key Laboratory of Clinical and Basic Research for Psychiatric Diseases, and School of Public Health, Zhejiang University School of Medicine, Hangzhou, China.ORCID https://orcid.org/0000-0003-3992-5812

Funding

European Commission, DG RTD through FP5 QLK6-CT-2001-00360FP6 SHARE-I3: RII-CT-2006-062193 COMPARE: CIT5-CT-2005-028857 SHARELIFE: CIT4-CT-2006-028812FP7 DASISH: GA N°283646FP7 SHARE-LEAP: GA N°227822FP7 SHARE M4: GA N°261982FP7 SHARE-PREP: GA N°211909German Federal Ministry of Research, Technology and Space 01UW1301 01UW1801 01UW2202Horizon 2020 SHARE-DEV3: GA N°676536 SHARE-COHESION: GA N°870628 SERISS: GA N°654221 SSHOC: GA N°823782 SHARE-COVID19: GA N°101015924Max Planck Society for the Advancement of Science, the U.S. National Institute on Aging U01_AG09740-13S2 P01_AG005842 P01_AG08291 P30_AG12815 R21_AG025169 Y1-AG-4553-01 IAG_BSR06-11 OGHA_04-064 BSR12-04 R01_AG052527-02 R01_AG056329-02 R01_AG063944 HHSN271201300071C RAG052527ANational Natural Science Foundation of China 72504248 to Z.CNational Natural Science Foundation of China 82570128 to X.T.Novo Nordisk Foundation NNF23OC0081873 to C.B. and NNF25OC0101995 to J.CPioneer R&D Programme of Zhejiang Province 2025C01119 to X.TRut and Arvid Wolff Memorial Foundation 2023-02467 to X.T
6 · The paper itself

Abstract

Circadian rhythms coordinate physiology with the 24 h light-dark cycle, and their disruption contributes to diseases spanning metabolic, cardiovascular, and neuropsychiatric domains. Whether the temporal coherence between wearable-derived activity and temperature rhythms predicts long-term health outcomes in free-living humans remains unknown. Here, analyzing week-long concurrent wrist-worn acceleration and device temperature recordings from approximately 90,000 UK Biobank participants (median age 63 years), we decompose the circular cross-correlation between behavioral and device temperature signals into three alignment features, including 24 h coupling strength (M

Indexed as

circadian disruptiondiurnal alignmentphenome‐wide association studyprospective cohortwearable accelerometry

Identifiers

PMID42318644
PMCPMC13337042

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.