Evidence map›Paper›PMID 42319100›Full record

Trial reportThe journal of extra-corporeal technology2026

Evaluation of accuracy of platelet rich plasma preparation devices for cardiac surgery: A prospective, randomized, single blinded study.

Larry Garrison, Daniel Nicks, Samantha Nicks, Jonah Green, Huong Pham, Steve Wysocki

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The journal of extra-corporeal technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Larry GarrisonFranciscan Health Indianapolis, Indianapolis, Indiana, USA.ORCID 0000-0002-9752-5019
Daniel NicksFranciscan Health Indianapolis, Indianapolis, Indiana, USA.
Samantha NicksFranciscan Health Indianapolis, Indianapolis, Indiana, USA.
Jonah GreenFranciscan Health Indianapolis, Indianapolis, Indiana, USA.
Huong PhamFranciscan Health Indianapolis, Indianapolis, Indiana, USA.
Steve WysockiFranciscan Health Indianapolis, Indianapolis, Indiana, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundApplying platelet rich plasma (PRP) to the sternum immediately prior to approximation has been shown to enhance wound healing, lower the incidence of sternal wound infections, reduce costs associated with treating these infections and decrease post-operative pain scores. Multiple investigations have reported device specific outcomes regarding PRP preparation yields from healthy volunteer blood donors, all with initial platelet counts in the normal range. What is missing from the literature is how accurately PRP preparations reflect device-specific yield target values, particularly under the clinical conditions encountered routinely in the cardiac surgery arena.

methodsThe Magellan

resultsIndividual yields from each tested device demonstrated some degree of limited variability. However, both groups mean values achieved and slightly exceeded the target value of a six-fold increase; Magellan group (M = 6.58, SD = 1.33), Angel group (M = 6.31, SD = 0.93).

conclusionBoth devices, on average, appear capable of accurately preparing PRP to meet the specific target value of a six-fold increase over baseline under conditions routinely encountered in cardiac surgery.

Indexed as

Cardiac Surgical ProceduresPlatelet-Rich PlasmaEquipment Failure AnalysisFemaleHumansMalePlatelet CountProspective StudiesReproducibility of ResultsSingle-Blind MethodCardiac surgeryCellular concentrationPlatelet-derived growth factorsPlatelet rich plasma

Identifiers

PMID42319100
PMCPMC13281295

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.