Evidence map›Paper›PMID 42320282›Full record

ArticleCellular immunology2026

Persistent CD4

Jadith Ziegler, Christina Lawrence, Nathan Pezant, Sean Turner, Nancy Redinger, Carla Guthridge, Kenneth Smith, Jingrong Chen, Joel M Guthridge, Judith A James and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jadith ZieglerArthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, USA.
Christina LawrenceArthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, USA.
Nathan PezantCenter for Biomedical Data Sciences, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, USA.
Sean TurnerArthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, USA.
Nancy RedingerArthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, USA.
Carla GuthridgeArthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, USA.
Kenneth SmithArthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, USA.
Jingrong ChenCell Cycle and Cancer Biology Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, USA.
Joel M GuthridgeArthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, USA; Department of Pathology, University of Oklahoma Health Campus, 1100 N Lindsay Ave, Oklahoma City, OK, USA.
Judith A JamesArthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, USA; Department of Microbiology & Immunology, University of Oklahoma Health Campus, 1100 N Lindsay Ave, Oklahoma City, OK, USA; Department of Pathology, University of Oklahoma Health Campus, 1100 N Lindsay Ave, Oklahoma City, OK, USA.
Susannah RankinCell Cycle and Cancer Biology Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, USA; Department of Cell Biology, University of Oklahoma Health Campus, 1100 N Lindsay Ave, Oklahoma City, OK, USA.
Linda F ThompsonArthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, USA; Department of Microbiology & Immunology, University of Oklahoma Health Campus, 1100 N Lindsay Ave, Oklahoma City, OK, USA.
A Darise FarrisArthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, USA; Department of Microbiology & Immunology, University of Oklahoma Health Campus, 1100 N Lindsay Ave, Oklahoma City, OK, USA; Department of Pathology, University of Oklahoma Health Campus, 1100 N Lindsay Ave, Oklahoma City, OK, USA. Electronic address: Darise-Farris@omrf.org.
Susan KovatsArthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK, USA; Department of Microbiology & Immunology, University of Oklahoma Health Campus, 1100 N Lindsay Ave, Oklahoma City, OK, USA; Department of Pathology, University of Oklahoma Health Campus, 1100 N Lindsay Ave, Oklahoma City, OK, USA. Electronic address: Susan-Kovats@omrf.org.

Funding

Translation of immunologic technologies from basic research into pre-clinical nonU19AI062629 · NIAID · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI FARRIS, A DARISE · 2004 to 2023
$56.2M
NIAID NIH HHS U19 AI062629
6 · The paper itself

Abstract

Symptoms of acute SARS-CoV-2 infection often resolve quickly but are sometimes associated with persistent immune dysfunction. The factors that predispose individuals to compromised immune function have not been well defined. We investigated CD4

Indexed as

CD4-Positive T-LymphocytesCOVID-19SARS-CoV-2AdultCD8-Positive T-LymphocytesCytokinesEnterotoxinsFemaleHumansInterleukin-7Lymphocyte ActivationMaleMiddle AgedReceptors, Antigen, T-CellCytokinesenterotoxin B, staphylococcalEnterotoxinsInterleukin-7Receptors, Antigen, T-CellCD4 T cellsSARS-CoV-2T cell hyporesponse

Identifiers

PMID42320282
PMCPMC13405433

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.