ReviewJournal of cancer survivorship : research and practice2026
Effects of exercise interventions on sarcopenia-related outcomes in cancer patients and survivors: an umbrella review of systematic reviews and meta-analyses.
Review in Journal of cancer survivorship : research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
Funding
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Abstract
purposeThis umbrella review systematically evaluate and synthesize current evidence for improving sarcopenia-related outcomes (muscle mass, strength, physical function) in cancer patients and survivors, to inform evidence-based exercise recommendations.
methodsWe searched PubMed, Embase, Web of Science, and Cochrane Library (Jan 2010-Dec 2025) for systematic reviews/meta-analyses of exercise interventions targeting sarcopenia-related outcomes in cancer patients and survivors. Two reviewers screened studies, extracted data, and assessed quality via AMSTAR 2. High heterogeneity led to content analysis instead of quantitative synthesis.
resultsFourteen eligible studies covering 16,406 cancer patients and survivors (breast, colorectal, liver cancer, etc.) were included. Content analysis revealed: 1) 4 studies indicated combined exercise (resistance + aerobic) provided the most comprehensive benefits (e.g., optimized body composition, reduced cancer-related fatigue); 2) 9 studies showed resistance training excelled in improving lean muscle mass and strength; 3) 1 study found aerobic exercise better enhanced functional capacity; 4) 1 study incorporating balance/flexibility training and home-based exercise reported improved muscular outcomes.
conclusionsCombined exercise is first-line for improving sarcopenia-related outcomes in cancer patients and survivors. However, the small volume of published reviews focusing on this modality should be noted, as it may compromise the reliability of this conclusion; Resistance training is preferred for standalone muscle mass preservation; Aerobic exercise suits patients with poor physical status. Individualized protocols should align with cancer type, treatment phase, and tolerance. High-quality studies are needed to define optimal exercise dosage.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.