Evidence map›Paper›PMID 42321952›Full record

ArticleBMC nutrition2026

The impact of calcium supplementation on hypertension management in postmenopausal women with hypocalcemia.

Ahmed Farouk Alaarag, Mohamed Naseem, Haidy Khattab, Reham Younis, Ahmed Hamam, Hazem K Shalaby, Mahmoud Abd Elkhalek Abou-Omar

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Article in BMC nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ahmed Farouk AlaaragDepartment of Cardiology, Tanta University, Tanta, Egypt. ahmed.elaarag@med.tanta.edu.eg.
Mohamed NaseemDepartment of Cardiology, Tanta University, Tanta, Egypt.
Haidy KhattabDepartment of Medical Physiology, Tanta University, Tanta, Egypt.
Reham YounisDepartment of Medical Physiology, Tanta University, Tanta, Egypt.
Ahmed HamamDepartment of Endocrinology and Metabolism, Armed Forces College of Medicine, Cairo, Egypt.
Hazem K ShalabyDepartment of Cardiology, Tanta University, Tanta, Egypt.
Mahmoud Abd Elkhalek Abou-OmarDepartment of Cardiology, Tanta University, Tanta, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypertension poses a significant health risk for postmenopausal women, with incidence rates notably higher than for men of the same age group. The decline in estrogen levels leads to several physiological changes, such as hypocalcemia, which may contribute to the development of hypertension. This study investigates the effects of calcium supplementation on blood pressure control in postmenopausal women with hypocalcemia.

methodsWe prospectively included 300 postmenopausal women diagnosed with both hypocalcemia and hypertension. The participants received calcium carbonate (1,000 mg/day) in two daily doses, in addition to their standard antihypertensive treatment. Blood pressure measurements and serum calcium levels were recorded at baseline and after 3 months. Patients were divided into two groups according to serum calcium level at 3 months: those with normalized calcium levels and those who continued hypocalcemia.

resultsWomen with persistent hypocalcemia at follow-up were younger at the age of menopause (mean age 48.65 years) compared to those who achieved normocalcemia (mean age 49.44 years), P = 0.017. Those who had normocalcemia had a significant SBP, DBP, and more patients achieved target blood pressure ( 0.017, 0.029 & 0.012), respectively.

conclusionsUse of calcium supplements to correct hypocalcemia in postmenopausal hypertensive women may help reduce blood pressure and achieve the target blood pressure.

Indexed as

HypertensionHypocalcemiaPost menopauseTarget blood pressure

Identifiers

PMID42321952
PMCPMC13282864

What Socratic holds

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LicenceCC BY-NC-ND
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