ArticleJournal of the American Geriatrics Society2026
Clinical Benefit and Remaining Risks of Kidney Transplantation in Older Patients: A Matched Comparison With CKD Patients.
Article in Journal of the American Geriatrics Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
backgroundAlthough kidney transplantation (KT) is associated with survival benefit compared with dialysis, even in older patients with end-stage kidney disease (ESKD), the magnitude of this benefit, non-mortality outcomes, and residual complications remain unclear. Comparisons with patients diagnosed with non-dialysis-dependent chronic kidney disease (CKD) can better clarify these issues.
methodsOlder KT recipients and patients with CKD were enrolled from a prospective nationwide database (N = 817) and the National Health Insurance Service-Senior Cohort Database (N = 14,185), respectively. A 1:1 matching was performed. All-cause mortality, cardiovascular events, progression to ESKD, infection-related hospitalizations, and cancer were compared.
resultsEach group comprised 802 matched patients; 115 deaths, 25 cardiovascular events, 40 ESKD events, and 288 infection-related hospitalizations occurred over a median follow-up period of 88 months. Cumulative incidences of mortality and cardiovascular events were comparable between groups, whereas progression to ESKD and infection-related hospitalizations were higher in older KT recipients than in patients with CKD. In multivariable Cox analysis, older KT recipients had similar risks of all-cause mortality (adjusted hazard ratio [HR] 0.57, 95% confidence interval [CI] 0.33-1.01) and cardiovascular events (1.31, 0.42-4.05) to older patients with CKD but had increased risks of progression to ESKD (3.51, 1.07-11.5) and infection-related hospitalizations (3.91, 2.66-5.74). HR of incident cancer was similar between groups (1.35, 0.75-2.46).
conclusionsOlder KT recipients did not demonstrate increased risks of all-cause mortality, cardiovascular events, or incident cancer compared with the matched CKD population but had higher risks of kidney failure and infection-related hospitalization.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.