ArticleAnalytical and bioanalytical chemistry2026
Differentiation of wild-type and PAP1-overexpressing tobacco by volatile organic compound profiling using TP-SESI mass spectrometry.
Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Real-time profiling of plant volatiles provides insight into metabolic regulation, yet rapid and high-throughput characterization remains analytically challenging. Here, we apply temperature programming secondary electrospray ionization (TP-SESI) mass spectrometry to compare volatile organic compound (VOC) profiles from wild-type and PAP1-overexpressing tobacco (Nicotiana tabacum). This study extends the application of TP-SESI, which was originally developed for plant volatile analysis, to evaluate genotype-specific metabolic differences. TP-SESI enabled sensitive detection of VOCs and semi-volatile compounds spanning three major plant volatile classes: terpenoids, phenylpropanoids/benzenoids, and fatty acid derivatives, across both genotypes. While the two genotypes shared many detected features, PAP1-overexpressing plants were associated with upregulation of these indicated VOCs, suggesting broad metabolic reprogramming associated with PAP1 activation. Statistical analyses revealed clear separation between genotypes, demonstrating TP-SESI captures robust, reproducible metabolic differences in intact plant tissue. These results suggest that TP-SESI is capable of detecting genotype-associated variations in plant volatile emissions and may be useful for examining transcription factor-related changes in plant metabolism.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.