Evidence map›Paper›PMID 42322437›Full record

SynthesisLasers in medical science2026

Photobiomodulation and sleep quality: systematic review and meta-analysis.

Wellington Marcos Vital de Azevedo, Kevlin de Souza, Maria Luiza Defante, Afonso Shiguemi Inoue Salgado, Rodrigo Álvaro Brandão Lopes-Martins, Sérgio Gomes da Silva, Francisco Gonzalez-Lima, Fabrizio Dos Santos Cardoso

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Lasers in medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wellington Marcos Vital de AzevedoHospital São Vicente de Paulo (HSVP), Bom Jesus do Itabapoana, Brazil.
Kevlin de SouzaHospital São Vicente de Paulo (HSVP), Bom Jesus do Itabapoana, Brazil.
Maria Luiza DefanteHospital São Vicente de Paulo (HSVP), Bom Jesus do Itabapoana, Brazil.
Afonso Shiguemi Inoue SalgadoNatural Quanta Wellness Center, Orlando, USA.
Rodrigo Álvaro Brandão Lopes-MartinsUniversidade Brasil, São Paulo, Brazil.
Sérgio Gomes da SilvaHospital do Câncer de Muriaé, Fundação Cristiano Varella (FCV), Muriaé, Brazil.
Francisco Gonzalez-LimaThe University of Texas at Austin, Austin, USA.
Fabrizio Dos Santos CardosoHospital São Vicente de Paulo (HSVP), Bom Jesus do Itabapoana, Brazil. fabrizioscardoso@yahoo.com.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep disturbances are increasingly prevalent and associated with altered brain metabolism and neuroinflammation. Photobiomodulation, a non-invasive technique using red or near-infrared light, can modulate mitochondrial activity, cerebral perfusion, and glial function, suggesting potential benefits for sleep regulation. This systematic review and meta-analysis evaluated the effects of photobiomodulation on sleep quality in clinical and experimental populations. A comprehensive search was performed in PubMed, Embase, and Cochrane databases through September 2025 using the terms (photobiomodulation OR "low level laser therapy") AND sleep. Five randomized controlled trials involving 240 participants met inclusion criteria. The pooled analysis suggested that photobiomodulation improved the Pittsburgh Sleep Quality Index (PSQI) scores compared with sham-control (MD = - 1.25; 95% CI - 2.38 to - 0.11; p = 0.03, I

Indexed as

Low-Level Light TherapySleep QualitySleep Wake DisordersHumansMitochondriaRandomized Controlled Trials as TopicRed LightLow-level laser therapyMitochondrial metabolismPhotobiomodulationSleep qualityTherapy for sleep disturbances

Identifiers

PMID42322437
PMCPMC13283139

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.