Evidence map›Paper›PMID 42323339›Full record

ArticleTranslational psychiatry2026

Hydrogen sulfide mitigates spatial learning deficits in angiotensin II-Induced hypertension via inhibition of endothelial NOX2 and neuroinflammation.

Gaurav Kumar, Shalini Mishra, Shyamal Goswami, Manish Sharma

Abstract read
In one paragraph

Article in Translational psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gaurav KumarSchool of Life Sciences and Biotechnology, Chhatrapati Shahu Ji Maharaj University, Kanpur, UP, 208024, India. gauravk@csjmu.ac.in.ORCID http://orcid.org/0000-0001-8884-1653
Shalini MishraDefence Institute of Physiology and Allied Sciences (DIPAS), Defence Research and Development Organization (DRDO), Delhi, India.
Shyamal GoswamiSchool of Life Sciences, Jawaharlal Nehru University (JNU), New Delhi, India.
Manish SharmaDefence Institute of Physiology and Allied Sciences (DIPAS), Defence Research and Development Organization (DRDO), Delhi, India. manishks77@gmail.com.ORCID http://orcid.org/0000-0003-4066-0823

Funding

Department of Science and Technology, Ministry of Science and Technology (DST) SERB- National Postdoctoral Fellowship [Grant number pdf/2016/003808]Indian Council of Medical Research (ICMR) ICMR RA 2019
6 · The paper itself

Abstract

Hypertension (HTN), when prolonged, extends beyond the cardiovascular system, impairs neurovascular function, and progresses into cognitive impairment. Thus, it is essential to understand the mechanism that drives HTN-induced brain pathogenesis for devising novel therapy. This study explored spatial learning, vessels-associated microglia and neuroinflammation during angiotensin II (Ang II) induced HTN with the hypothesis that after HTN induction, endogenous H

Indexed as

Hydrogen SulfideHypertensionNADPH Oxidase 2Neuroinflammatory DiseasesSpatial LearningAngiotensin IIAnimalsDisease Models, AnimalHippocampusMaleMicrogliaRatsRats, Sprague-DawleyAngiotensin IICybb protein, ratHydrogen SulfideNADPH Oxidase 2

Identifiers

PMID42323339
PMCPMC13530184

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.