Evidence mapPaperPMID 42323744Full record

ArticleArchives of gynecology and obstetrics2026

Pain and functional outcomes after surgical versus hormonal treatment in rectovaginal endometriosis: a retrospective cohort study.

Franziska Werner, Renata Voltolini Velho, Sylvia Mechsner

Abstract readComparative Study
In one paragraph

Article in Archives of gynecology and obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Franziska WernerDepartment of Gynaecology Charité with Centre of Oncological Surgery, Endometriosis Research Centre Charité, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany.ORCID 0009-0007-1088-1349
Renata Voltolini VelhoDepartment of Gynaecology Charité with Centre of Oncological Surgery, Endometriosis Research Centre Charité, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany.ORCID 0000-0003-0788-1640
Sylvia MechsnerDepartment of Gynaecology Charité with Centre of Oncological Surgery, Endometriosis Research Centre Charité, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany. sylvia.mechsner@charite.de.ORCID 0000-0002-1095-0048

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare changes in pain-related symptoms, bowel and bladder function, rectal bleeding, quality of life, and treatment satisfaction in women with rectovaginal endometriosis treated either surgically or with hormonal treatment alone in a tertiary referral centre.

methodsThis retrospective cohort study included women with rectovaginal endometriosis treated at a tertiary endometriosis centre with either surgical excision or hormonal treatment alone after informed consent. Standardised questionnaires assessed pain, functional symptoms, quality of life, and treatment satisfaction. Symptom changes were categorised as improvement, stability, or worsening. Between-group comparisons were performed using Mann-Whitney U tests and Pearson's chi-square tests, with effect sizes reported (r or Cramér's V). The analysis was exploratory.

resultsA total of 210 women were included (surgical n = 164; hormonal n = 46). Baseline pain intensity did not differ significantly between groups, although bowel dysfunction and rectal bleeding were more prevalent in the surgical cohort. Following treatment, approximately 80% of women in both groups reported improvement in pelvic pain and dysmenorrhoea. Improvements in dyspareunia, dyschezia, and functional outcomes were observed in substantial proportions. Between-group comparisons revealed no statistically significant differences in change categories across pain, functional symptoms, quality of life, or treatment satisfaction (all p ≥ 0.08), with consistently small effect sizes.

conclusionBoth surgical and hormonal treatment were associated with substantial improvements in patient-reported outcomes in women with rectovaginal endometriosis. Direct comparison revealed no significant differences in outcome trajectories, supporting an individualised treatment approach.

Indexed as

EndometriosisRectal DiseasesVaginal DiseasesAdultDysmenorrheaDyspareuniaFemaleHumansPatient SatisfactionPelvic PainQuality of LifeRetrospective StudiesTreatment OutcomeDeep-infiltrating endometriosisEndometriosisHormonal therapyPelvic painRectovaginal endometriosisSurgical treatment

Identifiers

PMID42323744
PMCPMC13284012

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.