ArticlePediatrics international : official journal of the Japan Pediatric Society
Redox Profile, Inflammatory and Cardiac Autonomic Nervous Activity of Children and Adolescents With Cystic Fibrosis.
Article in Pediatrics international : official journal of the Japan Pediatric Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCystic fibrosis (CF) is a genetic disease in which oxidative stress, chronic inflammation, and autonomic imbalance drive the pathophysiology; however, their interplay in children and adolescents with CF remains unclear. This study aimed to compare the cardiometabolic profile of children and adolescents with CF and healthy controls, and to investigate associations between heart rate variability (HRV), Forced Expiratory Volume in the first second (FEV
methodsThis cross-sectional study included 12 patients with CF and 12 healthy controls (5-18 years). Were analyzed for oxidative stress markers (total antioxidant capacity-CAOx, malondialdehyde-MDA), and inflammatory (hs-CRP, IL-2, IL-4, IL-6, IL-10, IL-17A, IFN-γ, and TNF-α). HRV was assessed using a Bluetooth heart rate monitor.
resultsMean age was similar between groups (CF: 11.7 ± 4.5 years vs. CONT: 12.5 ± 4.2 years, p = 0.68). Mean FEV
conclusionChildren and adolescents with CF exhibit increased oxidative stress, systemic inflammation, and reduced sympathetic and parasympathetic activity, as well as associations among lung function, HRV, and antioxidant capacity.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.