Evidence map›Paper›PMID 42325786›Full record

ArticleAmerican journal of translational research2026

Analysis of the effectiveness of the myocardial work index in the assessment of cancer therapy-related cardiac dysfunction.

Hui Ran, Yajing Miao, Yuming Zhang, Heping Deng, Feng Li

Abstract read
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Article in American journal of translational research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Hui RanDepartment of Ultrasound, The Third Hospital of Hebei Medical University Shijiazhuang 050000, Hebei, China.
Yajing MiaoDepartment of Cardiac Ultrasound, The Second Hospital of Hebei Medical University Shijiazhuang 050000, Hebei, China.
Yuming ZhangDepartment of Ultrasound, The Third Hospital of Hebei Medical University Shijiazhuang 050000, Hebei, China.
Heping DengDepartment of Ultrasound, The Third Hospital of Hebei Medical University Shijiazhuang 050000, Hebei, China.
Feng LiDepartment of Oncology, The Third Hospital of Hebei Medical University Shijiazhuang 050000, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the correlation between myocardial global work index (GWI) and cancer therapy-related cardiac dysfunction (CTRCD) during chemotherapy for patients with thoracic tumors.

methodsA retrospective analysis was conducted on 87 patients with thoracic tumors who underwent chemotherapy at The Third Hospital of Hebei Medical University from April 2022 to June 2023. Among them, 37 patients who developed CTRCD during chemotherapy were assigned to the research group, and the remaining 50 patients without CTRCD were assigned to the control group. Myocardial GWI was compared between the two groups at three time points: before chemotherapy (T0), during chemotherapy cycle 3 (T1), and upon completion of chemotherapy (T2). The predictive value of myocardial GWI at T0 and T1 for CTRCD was analyzed. Patients were followed up for prognosis, and the relationship between myocardial GWI at T2 and the recovery from CTRCD was evaluated. Additionally, the correlation between myocardial GWI and Creatine Kinase-MB (CK-MB) and cardiac troponin T (cTnT) at T0-T2 was analyzed.

resultsThe myocardial GWI in the research group was lower than that in the control group at T0-T2 (

conclusionMyocardial GWI is a reliable predictor for the occurrence of CTRCD during chemotherapy in patients with thoracic tumors, providing valuable clinical insights.

Indexed as

cancer therapy-related cardiac dysfunctioncardiac troponin Tchemotherapycreatine kinase-MBMyocardial global work indexthoracic tumors

Identifiers

PMID42325786
PMCPMC13275847

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.