Evidence map›Paper›PMID 42326405›Full record

ArticleFrontiers in microbiology2026

Genomic insights into probiotic potential and metabolic adapability of food derived

Tariq Aziz, Chasheen Fizza, Liqing Zhao, Zhennai Yang, Layla A Alahmari, Fatma Alshehri, Ashwag Shami, Omniah A Mansouri

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tariq AzizDepartment of Food Science and Technology, College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, Guangdong, China.
Chasheen FizzaDepartment of Food Science and Technology, College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, Guangdong, China.
Liqing ZhaoDepartment of Food Science and Technology, College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, Guangdong, China.
Zhennai YangKey Laboratory of Geriatric Nutrition and Health of Ministry of Education, Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing, China.
Layla A AlahmariDepartment of Community Health, College of Applied Medical Sciences, Northern Border University, Arar, Saudi Arabia.
Fatma AlshehriDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Ashwag ShamiDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Omniah A MansouriDepartment of Biological Sciences, Collage of Science, University of Jeddah, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Probiotic lactic acid bacteria derived from agro-food sources play a pivotal role in promoting human health and advancing functional food development, however the genomic determinants underlying their adaptive versatility and probiotic functionality remain insufficiently characterized. Methodology: The current study employs a comparative genomics framework to evaluate the genetic diversity, metabolic plasticity, and evolutionary trajectories of Results: NMGL2 exhibited the largest genome of 3.46 Mb among these strains, while having a total of 3,402 genes together with plasmids, which enhanced metabolic flexibility. A total of 59 genes were found which are likely linked with the functions of probiotic-related traits such as adhesion, immune modulation, and stress response. Although 59 genes were identified to be linked to probiotic characteristics like adhesion, immunomodulation, and stress resistance, the identified genomic features reflect the potential functionality and do not necessarily result in phenotypes. Discussion: The effectiveness of a probiotic is assessed based on more than just the availability of these genes; their regulation and expression are crucial.

Indexed as

comparative genomicsfood biotechnologyfunctional annotationlactic acid bacteria (LAB)metabolic plasticity

Identifiers

PMID42326405
PMCPMC13281585

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.