Evidence map›Paper›PMID 42326556›Full record

ReviewLancet regional health. Americas2026

Implementation of stroke prevention: a review of challenges and opportunities in the Americas.

Sheila O Martins, Pedro Ordunez, Wyllians Vendramini Borelli, Bruce Ovbiagele, Victor C Urrutia, Carlos Abanto, Matias J Alet, Bassel Almarie, Tony Fabián Alvarez, Pablo Amaya and 35 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Lancet regional health. Americas, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

45 authors.

Sheila O MartinsDepartment of Neurology and Neurosurgery, Hospital Moinhos de Vento, Porto Alegre, Brazil.
Pedro OrdunezDepartment of Noncommunicable Diseases and Mental Health, Pan American Health Organization, Washington, DC, USA.
Wyllians Vendramini BorelliNeurology Department, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
Bruce OvbiageleDepartment of Neurology, University of California San Francisco Weill Institute for Neurosciences, San Francisco, CA, USA.
Victor C UrrutiaDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Carlos AbantoThe Cerebrovascular Disease Research Center, National Institute of Neurological Sciences, Lima, Peru.
Matias J AletDepartamento de Neurología Vascular, Centro Integral de Neurología Vascular, Fleni, Ciudad Autónoma de Buenos Aires, Argentina.
Bassel AlmarieNeuromodulation Center and Center for Clinical Research Learning, Spaulding Rehabilitation Hospital and Massachusetts General Hospital, Harvard Medical School, MA, USA.
Tony Fabián AlvarezCentro de Excelencia en ACV, Instituto Neurológico, Hospital Internacional de Colombia-FCV, Colombia.
Pablo AmayaStroke Program, Neurology Department, Fundación Valle del Lili, Cali, Colombia.
Sebastian AmerisoDepartamento de Neurología Vascular, Centro Integral de Neurología Vascular, Fleni, Ciudad Autónoma de Buenos Aires, Argentina.
Antonio ArauzInstituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, México City, Mexico.
Miguel A BarbozaDepartamento de Neurociencias, Hospital Dr. Rafael A. Calderón Guardia, Universidad de Costa Rica, San José, Costa Rica.
Hernán BayonaUniversidad de los Andes School of Medicine, Bogotá, Colombia.
Juan CallejaInstituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, México City, Mexico.
Vanessa Cano-NigendaInstituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, México City, Mexico.
Leonardo Augusto CarboneraDepartment of Neurology and Neurosurgery, Hospital Moinhos de Vento, Porto Alegre, Brazil.
Rodrigo M Carrillo-LarcoEmory Global Diabetes Research Center and Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, USA.
Freddy ConstanzoNeurology Unit, Hospital Las Higueras, Talcahuano, Chile.
Angel CorredorDepartment of Neurology, Stroke Center, Clínica Central del Quindío, Armenia, Colombia.
Ana Cláudia de SouzaDepartment of Neurology and Neurosurgery, Hospital Moinhos de Vento, Porto Alegre, Brazil.
Jose Danilo DiestroUnity Health - St. Michael's Hospital, Li Ka Shing Knowledge Institute, University of Toronto, Toronto, Canada.
Felipe FregniNeuromodulation Center and Center for Clinical Research Learning, Spaulding Rehabilitation Hospital and Massachusetts General Hospital, Harvard Medical School, MA, USA.
Rodrigo GuerreroDepartment of Neurology, Neurosurgery and Interventional Neuroradiology, Clínica Santa María, Santiago, Chile.
Claudio JimenezStroke Center, Hospital Simón Bolívar, Subred Norte, Bogotá, Colombia.
Fernando LanasDepartment of Internal Medicine, Faculty of Medicine, Universidad de la Frontera, Temuco, Chile.
Ramón MartinezDepartment of Noncommunicable Diseases and Mental Health, Pan American Health Organization, Washington, DC, USA.
Carla MoroDepartamento de Neurologia, Hospital Municipal São José, Joinville, SC, Brazil.
Paula Muñoz-VenturelliCentro de Estudios Clínicos, ICIM, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile.
Victor NaviaCentro de Estudios Clínicos, ICIM, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile.
Nelson Novarro-EscuderoPrimary Stroke Center, Pacífica Salud, Hospital Punta Pacífica, Panamá, Panama.
Verónica V OlavarríaServicio de Neurología, Departamento de Neurología y Psiquiatría, Clínica Alemana de Santiago, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile.
Antonio Bernabé-OrtizFaculty of Health Sciences, Universidad Científica del Sur, Lima, Peru.
Octavio Pontes-NetoDepartment of Neuroscience and Behavioral Sciences, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Virginia PujolDepartamento de Neurología Vascular, Centro Integral de Neurología Vascular, Fleni, Ciudad Autónoma de Buenos Aires, Argentina.
Alejandro A RabinsteinDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Julieta RosalesServicio de Neurología Vascular, Departamento de Neurología, Clínica La Sagrada Familia, Buenos Aires, Argentina.
Andres RosendeDepartment of Noncommunicable Diseases and Mental Health, Pan American Health Organization, Washington, DC, USA.
Gisele Sampaio SilvaNeurology Department, Universidade Federal de São Paulo (UNIFESP) and Albert Einstein Hospital, São Paulo, Brazil.
Gustavo SaposnikStroke Outcomes & Decision Neuroscience Research Unit, Department of Medicine, University of Toronto, Toronto, Canada.
Souvik SenDepartment of Neurology, University of South Carolina School of Medicine, Prisma Health Medical Group Midlands, Columbia, SC, USA.
Luciano SposatoCNS Dept. K. & Dr. Henry Barnett Chair in Stroke Research, Schulich School of Medicine & Dentistry, Western U. Director. Heart & Brain Lab, London, ON, Canada.
Fernando D TestaiDepartment of Neurology and Rehabilitation, University of Illinois Chicago College of Medicine, Chicago, IL, USA.
Craig S AndersonThe George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, Australia.
Pablo M LavadosServicio de Neurología, Departamento de Neurología y Psiquiatría, Clínica Alemana de Santiago, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke remains a leading cause of death and disability throughout the Americas, disproportionately impacting low-and middle-income countries and underserved populations. In this review, we examine the status of stroke prevention in the Americas. Prevention is essential, yet unequal access to healthcare has led to major disparities - especially among rural populations, ethnic minorities, and lower socioeconomic status. Models like the WHO HEARTS Program demonstrate that evidence-based programs can be tailored to local contexts. Telehealth and digital tools play a critical role in empowering patients, educating communities, and supporting healthcare workers. Despite growing efforts, challenges persist due to health inequities, gaps between policy and implementation, and underinvestment. Strengthening prevention will support countries in achieving the United Nations Sustainable Development Goals, targeting a one-third reduction in premature deaths from non-communicable diseases by 2030. This paper outlines effective strategies for implementing stroke prevention, emphasizing healthy lifestyles, early detection of risk factors, and system-level interventions.

Indexed as

Cardiovascular diseaseImplementationPrimary preventionSecondary preventionStroke

Identifiers

PMID42326556
PMCPMC13280441

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.