Evidence map›Paper›PMID 42327367›Full record

ArticleBrain communications2026

Tics severity in Tourette syndrome associated with higher glutamatergic activity in the anterior cingulate cortex.

Mathilde Boussac, Anne-Sophie Salabert, Estelle Harroch, Claire Thalamas, Christophe Arbus, Yves Chaix, Anne-Laure Toureille Pouget, Pierre Payoux, Christine Brefel-Courbon

Abstract read
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In one paragraph

Article in Brain communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mathilde BoussacToulouse Neuroimaging Centre (ToNIC), Inserm UMR1214, University of Toulouse III (UPS), 31059 Toulouse, France.ORCID https://orcid.org/0000-0002-3532-6743
Anne-Sophie SalabertToulouse Neuroimaging Centre (ToNIC), Inserm UMR1214, University of Toulouse III (UPS), 31059 Toulouse, France.
Estelle HarrochDepartment of Clinical Pharmacology and Neurosciences, Parkinson's Expert Centre, Toulouse University Hospital, NeuroToul COEN (Centre of Excellence in Neurodegeneration), 31059 Toulouse, France.
Claire ThalamasClinical Investigation Centre (CIC 1436), Department of Clinical Pharmacology, Toulouse University Hospital, 31059 Toulouse, France.
Christophe ArbusToulouse Neuroimaging Centre (ToNIC), Inserm UMR1214, University of Toulouse III (UPS), 31059 Toulouse, France.
Yves ChaixToulouse Neuroimaging Centre (ToNIC), Inserm UMR1214, University of Toulouse III (UPS), 31059 Toulouse, France.
Anne-Laure Toureille PougetDepartment of Paediatric Neurology, Children's Hospital, Toulouse University Hospital, 31059 Toulouse, France.
Pierre PayouxToulouse Neuroimaging Centre (ToNIC), Inserm UMR1214, University of Toulouse III (UPS), 31059 Toulouse, France.
Christine Brefel-CourbonToulouse Neuroimaging Centre (ToNIC), Inserm UMR1214, University of Toulouse III (UPS), 31059 Toulouse, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tourette syndrome is a neuropsychiatric disorder whose physiopathology is still poorly understood. It involves alterations in the dopaminergic system within the cortico-basal ganglia-thalamo-cortical loops although several hypotheses from the literature implicate the glutamatergic system. Our objective was to study the activity of NMDA receptors (NMDARs) in vivo in patients with Tourette syndrome compared to healthy controls. PET imaging was used in patients with Tourette syndrome (

Indexed as

anterior cingulate cortexglutamateNMDA receptorsPETTourette syndrome

Identifiers

PMID42327367
PMCPMC13281919

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.