Evidence map›Paper›PMID 42327433›Full record

ReviewCJC open2026

Pregnancy Management and Outcomes with Hypertrophic Cardiomyopathy.

Adhya Mehta, Sarah Schumacher, Rebekah Alison Bhansali, Yaa Adoma Kwapong, Yoo Jin Kim, Oluwalonimi Adebowale, Arthur Jason Vaught, Zahwa Awais, Farooq H Sheikh, Erin D Michos and 3 more

Abstract readReview
In one paragraph

Review in CJC open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Adhya MehtaInova Health System, Falls Church, Virginia, USA.
Sarah SchumacherCornell University, New York, New York, USA.
Rebekah Alison BhansaliJohns Hopkins School of Nursing, Baltimore, Maryland, USA.
Yaa Adoma KwapongJohns Hopkins School of Medicine, Baltimore, Maryland, USA.
Yoo Jin KimDuke University, Durham, North Carolina, USA.
Oluwalonimi AdebowaleJohns Hopkins School of Medicine, Baltimore, Maryland, USA.
Arthur Jason VaughtJohns Hopkins Medicine Obstetrics & Gynecology, Baltimore, Maryland, USA.
Zahwa AwaisMayo University Hospital, Castlebar Co., Mayo, Ireland.
Farooq H SheikhMedStar Health/Georgetown University School of Medicine, Washington, DC, USA.
Erin D MichosJohns Hopkins School of Medicine, Baltimore, Maryland, USA.
Jose MadrazoJohns Hopkins School of Medicine, Baltimore, Maryland, USA.
Allison G HaysJohns Hopkins School of Medicine, Baltimore, Maryland, USA.
Anum S MinhasJohns Hopkins School of Medicine, Baltimore, Maryland, USA.

Funding

Strength-Based Health Equity Across the Life CourseT32NR020315 · NINR · JOHNS HOPKINS UNIVERSITY · PI HAE-RA HAN · 2022 to 2026
$1.8M
NINR NIH HHS T32 NR020315
6 · The paper itself

Abstract

Hypertrophic cardiomyopathy (HCM) is a common inherited genetic cardiac disorder that increasingly is being diagnosed in people of childbearing age, due to advancements in genetic testing and the evolution of screening guidelines. Many women may first present with HCM during pregnancy, which can lead to adverse maternal and fetal outcomes if not appropriately managed. Although most women with HCM tolerate pregnancy well, it can be associated with increased cardiovascular risks, including heart failure, arrhythmias, and adverse fetal outcomes, particularly among those with suboptimal baseline functional status. Medical therapy remains the mainstay of management of HCM in pregnancy, as only a limited number of studies have been done on the safety and effectiveness of invasive procedures, such as alcohol septal ablation and cardiac myomectomy, in pregnant women. Large cohort studies of women with HCM are very limited, and management practices vary within centres, with no protocolized care. This review aims to summarize the unique challenges faced by pregnant women with HCM, highlighting the need for large multicentric studies and more standardized care protocols to optimize maternal and fetal outcomes.

Indexed as

hypertrophic cardiomyopathypregnancy

Identifiers

PMID42327433
PMCPMC13282534

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.