Evidence map›Paper›PMID 42328457›Full record

ArticleInternational journal of biological sciences2026

Nicotinamide riboside reduces glial inflammation and boosts mitochondrial function.

Tsering Yangzom, Anbin Chen, Bjørn Christian Lundberg, Kristina Xiao Liang

Abstract read
In one paragraph

Article in International journal of biological sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tsering YangzomDepartment of Biomedicine (IBM), University of Bergen, Bergen, Norway.
Anbin ChenDepartment of Neurosurgery, Xinhua Hospital Affiliated with Shanghai Jiaotong University School of Medicine, Shanghai, China.
Bjørn Christian LundbergDepartment of Clinical Medicine (K1), University of Bergen, Bergen, Norway.
Kristina Xiao LiangDepartment of Biomedicine (IBM), University of Bergen, Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Astrocyte dysfunction plays a pivotal role in the pathogenesis of POLG-related mitochondrial diseases, yet the underlying mechanisms remain poorly understood. Here, we employed human iPSC-derived astrocytes, cortical organoids and astrocyte-neuron co-culture systems to model

Indexed as

AstrocytesInflammationMitochondriaNiacinamidePyridinium CompoundsCells, CulturedCoculture TechniquesDNA Polymerase gammaHumansNeuronsDNA Polymerase gammaNiacinamidenicotinamide-beta-ribosidePyridinium Compounds

Identifiers

PMID42328457
PMCPMC13282778

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.