Evidence map›Paper›PMID 42328874›Full record

ArticleJournal of bacteriology2026

Activation of the antibiotic resistance factor WhiB7 can stimulate aggregate biofilm formation in stationary phase

Mitchell D Meyer, Megan Bergkessel, William H DePas

Abstract read
In one paragraph

Article in Journal of bacteriology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mitchell D MeyerDepartment of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, USA.ORCID 0000-0001-6058-0738
Megan BergkesselDivision of Molecular Microbiology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.ORCID 0000-0002-4530-1224
William H DePasDepartment of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, USA.ORCID 0000-0001-8532-2567

Funding

The Impact of the Cystic Fibrosis infection environment on biofilm development of nontuberculous mycobacteriaR01AI170607 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI William H. DePas · 2023 to 2026
$1.6M
Academy of Medical Sciences SBF005/1096Cystic Fibrosis Foundation BOMBER21R3NIAID NIH HHS R01 AI170607NIH HHS R01-AI170607UK Research and Innovation MR/T041811/1
6 · The paper itself

Abstract

There is a growing understanding that slow growth and dormancy due to nutrient deprivation are very common physiological states exhibited by bacterial communities in a myriad of environments. However, very little is known about the role of slow growth and dormancy in biofilm regulation. Here, we utilize tractable dormancy and aggregation assays in nontuberculous mycobacteria (NTM) to ask the fundamental question of how growth arrest impacts the processes of aggregation and dispersal. First, we show that the well-conserved dormancy regulator DosSR affects biofilm formation in

Indexed as

Bacterial ProteinsBiofilmsMycobacterium smegmatisProtein BiosynthesisDrug Resistance, BacterialGene Expression Regulation, BacterialBacterial Proteinsantibiotic tolerancebiofilmsdormancyNTMtwo-component systems

Identifiers

PMID42328874
PMCPMC13393426

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.