Evidence map›Paper›PMID 42329416›Full record

ArticleAnnals of medicine2026

Association between preoperative prognostic nutritional index and postoperative delirium in older adults with hip fractures: a real-world study.

Qian Wu, Yongsheng Tian, Tianyu Zhao, Xiaolan Feng, Wenquan Ding, Huiji Xu, Chuchu Wang, Yahui Tong, Hongxia Zhu, Dinghau Jiang and 3 more

Abstract read
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In one paragraph

Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Qian WuDepartment of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, Institute of Orthopedics at Soochow University, Suzhou, China.ORCID 0000-0002-3986-6042
Yongsheng TianSuzhou Medical College, Soochow University, Suzhou, China.
Tianyu ZhaoSuzhou Medical College, Soochow University, Suzhou, China.
Xiaolan FengDepartment of Nursing, The First Affiliated Hospital of Soochow University, Suzhou, China.
Wenquan DingDepartment of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, Institute of Orthopedics at Soochow University, Suzhou, China.
Huiji XuDepartment of Nursing, The First Affiliated Hospital of Soochow University, Suzhou, China.
Chuchu WangDepartment of Nursing, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yahui TongDepartment of Nursing, The First Affiliated Hospital of Soochow University, Suzhou, China.
Hongxia ZhuDepartment of Nursing, The First Affiliated Hospital of Soochow University, Suzhou, China.
Dinghau JiangDepartment of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, Institute of Orthopedics at Soochow University, Suzhou, China.
Lixin HuangDepartment of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, Institute of Orthopedics at Soochow University, Suzhou, China.
Wu XuDepartment of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, Institute of Orthopedics at Soochow University, Suzhou, China.
Shenghao WangDepartment of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, Institute of Orthopedics at Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prognostic nutritional index (PNI), a marker reflecting nutritional and immunological status, has been proposed as a predictor of adverse postoperative outcomes. However, whether its association with postoperative delirium (POD) differs between femoral neck fractures and intertrochanteric fractures remains unclear.

methodsThis retrospective cohort study included patients aged ≥60 years who underwent hip fracture surgery between 2023 and 2024 PNI was calculated preoperatively, and POD was diagnosed during hospitalization using standardized clinical criteria. Analyses were conducted separately for femoral neck and intertrochanteric fracture groups for comparison. Restricted cubic spline (RCS), cox regression, subgroup analyses, receiver operating characteristic (ROC), propensity score matching (PSM), and Kaplan-Meier analyses were performed.

resultsA total of 339 patients with femoral neck fractures and 260 patients with intertrochanteric fractures were included in this study. A significant association between preoperative PNI and POD was observed in patients with femoral neck fractures. In patients with femoral neck fractures, RCS analysis demonstrated an approximately linear inverse relationship between PNI and POD risk (

conclusionA lower preoperative PNI was associated with an increased risk of POD among older adults with femoral neck fractures, but not among those with intertrochanteric fractures. PNI may serve as a simple tool for preoperative risk stratification in patients with femoral neck fractures.

Indexed as

DeliriumFemoral Neck FracturesHip FracturesNutrition AssessmentPostoperative ComplicationsAgedAged, 80 and overFemaleHumansKaplan-Meier EstimateMaleMiddle AgedNutritional StatusPreoperative PeriodPrognosisProportional Hazards Modelselderly patientsfemoral neck fracturesintertrochanteric fracturespostoperative deliriumPrognostic nutritional index

Identifiers

PMID42329416
PMCPMC13288896

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.