Evidence map›Paper›PMID 42329779›Full record

ArticleIntegrative and comparative biology2026

Navigating the Semantic Labyrinth of "Sex" in the Study of Reproductive Trait Evolution.

Caitlin E McDonough-Goldstein, Soleil E Young, Maurine Neiman, Sadye Paez, Nicole Valenzuela, Cibele G Sotero-Caio, Daniel L Jeffries, Octavio Manuel Palacios-Gimenez, Jessica K Abbott, Chiara Benvenuto and 9 more

Abstract read
In one paragraph

Article in Integrative and comparative biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Caitlin E McDonough-GoldsteinDepartment of Evolutionary Biology, University of Vienna, Vienna, 1030, Austria.ORCID 0000-0001-8949-7479
Soleil E YoungPlant and Microbial Sciences, University of California-Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-5309-7892
Maurine NeimanDepartment of Biology, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0002-1543-8115
Sadye PaezNeurogenetics of Language Laboratory, The Rockefeller University, New York City, NY 10065, USA.ORCID 0000-0003-0475-7871
Nicole ValenzuelaDepartment of Ecology, Evolution, and Organismal Biology, Iowa State University, Ames, Iowa 50011, USA.ORCID 0000-0003-1148-631X
Cibele G Sotero-CaioTree of Life Programme, Wellcome Sanger Institute, Hinxton, CB10 1RQ, UK.ORCID 0000-0002-3112-0000
Daniel L JeffriesInstitute of Ecology and Evolution, University of Bern, Bern, 3012, Switzerland.ORCID 0000-0003-1701-3978
Octavio Manuel Palacios-GimenezPopulation Ecology Group, Institute of Biodiversity, Ecology and Evolution, Friedrich Schiller Universität, Jena, 07743, Germany.ORCID 0000-0002-1472-9949
Jessica K AbbottDivision of Biodiversity and Evolution, Biology Department, Lund University, Lund, 223 62, Sweden.ORCID 0000-0002-8743-2089
Chiara BenvenutoSchool of Science, Engineering and Environment, University of Salford, Manchester, M5 4WT, UK.ORCID 0000-0002-8378-8168
Ann Kathrin HuylmansInstitute for Organismic and Molecular Evolution (iomE), Johannes Gutenberg-Universität Mainz, Mainz, 55128, Germany.ORCID 0000-0001-8871-4961
Sara CalhimDepartment of Biological and Environmental Science, University of Jyväskylä, Jyväskylä, FI-40014, Finland.ORCID 0000-0001-9059-2641
J Antonio BaezaDepartment of Biological Sciences, Clemson University, Clemson, SC 29634, USA.ORCID 0000-0002-2573-6773
Andrew J MongueDepartment of Entomology and Nematology, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Fl 32611, USA.ORCID 0000-0002-8487-9248
Erica L LarsonDepartment of Biological Sciences, University of Denver, Denver, CO 80208, USA.ORCID 0000-0003-3006-645X
Lucija AndjelLaboratory of Non-Mendelian Evolution, Institute of Animal Physiology and Genetics, The Czech Academy of Sciences, Liběchov, 277 21, Czech Republic.ORCID 0000-0002-5708-1433
Rainer MelzerSchool of Biology and Environmental Science, University College Dublin, Dublin, D04 V1W8, Ireland.ORCID 0000-0003-0631-9023
Elizabeth DietzCenter for Biology and Society, Arizona State University, Tempe, AZ 85287,USA.ORCID 0009-0007-9836-437X
Aurora Ruiz-HerreraDepartment de Biologia Cellular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, 08193, Spain.ORCID 0000-0003-3868-6151

Funding

Agència de Gestió d'Ajuts Universitaris i de Recerca 2021SGR00122Czech Science Foundation 24-12217SNational Science Foundation PRFB-2208973Spanish Ministry of Science and Innovation PID2020-112557GB-I00Spanish Ministry of Science and Innovation PID2024-156042NB-I00Swiss National Science Foundation 407023052
6 · The paper itself

Abstract

"Sex" is a compound of many different concepts that contribute to a multiplicity of meanings. As a result, "sex" appears in a wide range of scientific research for different purposes, from describing a process of recombination and cell division to systems of categorising individuals. Identifying the meaning of "sex" in any particular context requires understanding the construction of contributing component concepts and their relationship with one another. We offer the metaphor of a labyrinth to describe the process of interpreting the meaning "sex" and uncovering its context-dependent purpose. In this way, the meanings of "sex" related to "sexual reproduction", "sex types", "sex determination", and/or "sexual systems" can be elucidated by identifying how these concepts relate to suppositions about what properties of "recombination, "meiosis", "syngamy", or "gametes" are present and to which aspects of a trait, individual, or lineage they apply. By denoting "sex" and related terminology within quotation marks, we emphasise the contextualism of language in the theory and practise of research and resultant knowledge about the natural world. The structure of a labyrinth reflects the incredible capacity of "sex" to describe the diversity and disparity of eukaryotic reproductive strategies. The analytical framework of the labyrinth highlights that different conceptual versions can arise in the consideration of reproductive trait evolution based on the relationships among concepts. Through a critical evaluation of the concepts that contribute to the labyrinth of "sex" across biology, we gain a more nuanced appreciation for the operation of "sex" within scientific knowledge.

Indexed as

Biological EvolutionReproductionAnimalsTerminology as Topic

Identifiers

PMID42329779
PMCPMC13430665

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.