Evidence map›Paper›PMID 42330243›Full record

ArticleCartilage2026

In Vitro Cytotoxicity and Inflammatory Response of Local Anaesthetics and Corticosteroids in Canine Fibroblast-Like Synoviocytes.

Catarina Sousa, Ana Lima, Adriana Belas, Sónia Campos

Abstract read
In one paragraph

Article in Cartilage, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Catarina SousaI-MVET (Research in Veterinary Medicine), Faculty of Veterinary Medicine, Lusófona University - Lisbon University Center, Lisbon, Portugal.ORCID 0000-0001-5172-7806
Ana LimaI-MVET (Research in Veterinary Medicine), Faculty of Veterinary Medicine, Lusófona University - Lisbon University Center, Lisbon, Portugal.
Adriana BelasI-MVET (Research in Veterinary Medicine), Faculty of Veterinary Medicine, Lusófona University - Lisbon University Center, Lisbon, Portugal.
Sónia CamposI-MVET (Research in Veterinary Medicine), Faculty of Veterinary Medicine, Lusófona University - Lisbon University Center, Lisbon, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveThis study investigated the dose-dependent cytotoxicity and immunomodulatory effects of intra-articular local anaesthetics (lidocaine, mepivacaine, levobupivacaine) and corticosteroids (dexamethasone, methylprednisolone, methylprednisolone acetate) on canine fibroblast-like synoviocytes (FLS)

Indexed as

corticosteroidscytotoxicityfibroblast-like synoviocytesIL-6local anaestheticsMMP-9osteoarthritis

Identifiers

PMID42330243
PMCPMC13286958

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.