Evidence map›Paper›PMID 42330500›Full record

Trial reportAnnals of internal medicine2026

Expanding Technology-Enabled, Nurse-Delivered Chronic Disease Care : A Pragmatic, Randomized, Effectiveness-Implementation Trial.

Matthew J Crowley, Allison A Lewinski, Qing Yang, Daniel Hatch, Anushka Palipana, Hayden B Bosworth, Brystana G Kaufman, Ranee Chatterjee, Gina Pennington, Doreen Matters and 11 more

Registry-linked trialAbstract readRandomized Controlled TrialPragmatic Clinical TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Annals of internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05120544 (Expanding Technology-Enabled Nurse Delivered Chronic Disease Care), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05120544 nacompletednot on this map

Expanding Technology-Enabled Nurse Delivered Chronic Disease Care

TypeinterventionalSponsorDuke UniversityRan2022 to 2025Enrolled220ConditionsDiabetes Mellitus, Type 2, HypertensionArmsEXTEND Plus, EXTEND
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Matthew J CrowleyDivision of Endocrinology, Department of Medicine, Duke University School of Medicine, and Durham Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Medical Center, Durham, North Carolina (M.J.C., J.G.).ORCID 0000-0002-6205-4536
Allison A LewinskiDurham Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Medical Center, and School of Nursing, Duke University, Durham, North Carolina (A.A.L.).ORCID 0000-0002-1356-1857
Qing YangSchool of Nursing, Duke University, Durham, North Carolina (Q.Y., D.H., A.P., G.P., D.M., D.L., D.U., S.S., R.J.S.).ORCID 0000-0003-4844-4690
Daniel HatchSchool of Nursing, Duke University, Durham, North Carolina (Q.Y., D.H., A.P., G.P., D.M., D.L., D.U., S.S., R.J.S.).
Anushka PalipanaSchool of Nursing, Duke University, Durham, North Carolina (Q.Y., D.H., A.P., G.P., D.M., D.L., D.U., S.S., R.J.S.).ORCID 0000-0001-5237-1397
Hayden B BosworthDurham Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Medical Center; School of Nursing, Duke University; Division of General Internal Medicine, Department of Medicine, Duke University School of Medicine; and Department of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina (H.B.B.).
Brystana G KaufmanDurham Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Medical Center; Department of Population Health Sciences, Duke University School of Medicine; and Duke-Margolis Institute for Health Policy, Duke University, Durham, North Carolina (B.G.K.).
Ranee ChatterjeeDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, North Carolina (R.C.).ORCID 0000-0002-4294-8081
Gina PenningtonSchool of Nursing, Duke University, Durham, North Carolina (Q.Y., D.H., A.P., G.P., D.M., D.L., D.U., S.S., R.J.S.).
Doreen MattersSchool of Nursing, Duke University, Durham, North Carolina (Q.Y., D.H., A.P., G.P., D.M., D.L., D.U., S.S., R.J.S.).
Donghwan LeeSchool of Nursing, Duke University, Durham, North Carolina (Q.Y., D.H., A.P., G.P., D.M., D.L., D.U., S.S., R.J.S.).
Diana UrlichichSchool of Nursing, Duke University, Durham, North Carolina (Q.Y., D.H., A.P., G.P., D.M., D.L., D.U., S.S., R.J.S.).
Hailey N MillerSchool of Nursing, Johns Hopkins University, Baltimore, Maryland (H.N.M.).
Jashalynn GermanDivision of Endocrinology, Department of Medicine, Duke University School of Medicine, and Durham Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Medical Center, Durham, North Carolina (M.J.C., J.G.).ORCID 0000-0002-8091-1941
Somin SangSchool of Nursing, Duke University, Durham, North Carolina (Q.Y., D.H., A.P., G.P., D.M., D.L., D.U., S.S., R.J.S.).
Benjamin SmithDepartment of Pharmacy, Duke University Health System, Durham, North Carolina (B.S., P.G., C.L.R., H.C.).
Sarah KokosaDivision of Endocrinology, Department of Medicine, Duke University School of Medicine, and Department of Pharmacy, Duke University Health System, Durham, North Carolina (S.K.).
Patrick GregoryDepartment of Pharmacy, Duke University Health System, Durham, North Carolina (B.S., P.G., C.L.R., H.C.).ORCID 0000-0003-1412-0129
Cindy Leslie RobersonDepartment of Pharmacy, Duke University Health System, Durham, North Carolina (B.S., P.G., C.L.R., H.C.).ORCID 0009-0004-6836-8968
Holly CanuppDepartment of Pharmacy, Duke University Health System, Durham, North Carolina (B.S., P.G., C.L.R., H.C.).ORCID 0009-0004-7120-4171
Ryan J ShawSchool of Nursing, Duke University, Durham, North Carolina (Q.Y., D.H., A.P., G.P., D.M., D.L., D.U., S.S., R.J.S.).

Funding

CTSA UM1 at Duke UniversityUM1TR005436 · DUKE UNIVERSITY · 2025 to 2025
$9.9M
EXpanding Technology-Enabled, Nurse-Delivered Chronic Disease Care (EXTEND)R01NR019594 · NINR · DUKE UNIVERSITY · 2023 to 2025
$2.0M
NCATS NIH HHS UM1 TR005436NINR NIH HHS R01 NR019594
6 · The paper itself

Abstract

backgroundComprehensive telehealth is used effectively for treatment-resistant chronic diseases in certain integrated health systems but has seldom been implemented in systems that provide mainly fee-for-service (FFS) care.

objectiveTo examine the effectiveness and implementation of comprehensive telehealth delivered in an FFS environment for patients with uncontrolled type 2 diabetes (T2D) and comorbid hypertension.

designPragmatic, randomized, effectiveness-implementation trial. (ClinicalTrials.gov: NCT05120544).

setting6 academic primary care or endocrinology clinics.

participantsParticipants had both T2D with hemoglobin A

interventionTwo 12-month, mobile monitoring-enabled interventions: a self-monitoring control program and a nurse-delivered, comprehensive telehealth program incorporating self-management support and medication management. MEASUREMENTS: Primary (HbA

resultsParticipants were 64% female and 68% Black. The mean age was 54.5 years, mean HbA LIMITATION: Generalizability to dissimilar populations and systems lacking telehealth infrastructure may be limited.

conclusionComprehensive telehealth did not substantially lower HbA PRIMARY FUNDING SOURCE: National Institute of Nursing Research and Duke Clinical & Translational Science Institute.

Indexed as

Diabetes Mellitus, Type 2HypertensionTelemedicineAdherence InterventionsAgedChronic DiseaseDigital HealthFemaleGlycated HemoglobinHumansMaleMiddle AgedSelf CareGlycated Hemoglobin

Identifiers

PMID42330500
PMCPMC13374718

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.