Evidence map›Paper›PMID 42332573›Full record

ArticleBMC pregnancy and childbirth2026

Isolation, prevalence, and antimicrobial resistance profiles of Ureaplasma spp. and Mycoplasma hominis in cervical secretions from pregnant and postpartum women in Hangzhou, China.

Jiaming Ye, Xiaofang Xuan, Ke Xu, Meizhen Ye

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jiaming Ye *Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Xiaofang Xuan *Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital(Affiliated People's Hospital), Hangzhou Medical College, 158 Shangtang Road, Hangzhou, Zhejiang, 325000, China.
Ke XuLaboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital(Affiliated People's Hospital), Hangzhou Medical College, 158 Shangtang Road, Hangzhou, Zhejiang, 325000, China. 398894073@qq.com.
Meizhen YeCancer Center, Department of Hematology, Zhejiang Provincial People's Hospital(Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 325000, China. yeziyezi0123@126.com.

Funding

Zhejiang Medical and Health Science and Technology Program 2024KY712Zhejiang Medical and Health Science and Technology Program 2024KY755Zhejiang Medical and Health Science and Technology Program 2025KY606
6 · The paper itself

Abstract

objectiveTo evaluate the prevalence and antimicrobial resistance profiles of Ureaplasma spp. and Mycoplasma hominis in cervical secretions samples from pregnant and postpartum women in Hangzhou, China.

methodsWe performed a retrospective analysis of Ureaplasma spp. and Mycoplasma hominis culture positive rates and antimicrobial susceptibility patterns using 1,177 cervical secretion specimens, including 616 from pregnant women, 150 from postpartum women, and 411 from asymptomatic non-pregnant women attending routine gynecological check-ups. All secretion specimens were collected at Zhejiang Provincial People's Hospital clinical microbiology laboratory between January 2017 and July 2023.

resultsAmong 1,177 participants, the overall genital mycoplasma (Ureaplasma spp. and Mycoplasma hominis) colonization rate was 51.60% (607/1,177), with significantly higher prevalence in pregnant women (57.10%, 352/616) compared to other groups. The highest colonization rate occurred in pregnant adolescents < 20 years (66.70%, 4/6). Ureaplasma spp. was the predominant detected species (51.50%, 317/616 in pregnant women), while M. hominis colonization was rare (≤ 0.80% overall). Co-colonization (Ureaplasma spp. + M. hominis) was detected in 4.90% (30/616) of pregnant women. The highest in vitro resistance rates among all genital mycoplasma-positive isolates (Ureaplasma spp. and Mycoplasma hominis) were observed for gatifloxacin (80.26%, 122/152), ciprofloxacin (69.17%, 184/266), and roxithromycin (37.70%, 92/244).

conclusionUreaplasma spp. was the predominant genital mycoplasma colonizing pregnant and postpartum women in Hangzhou, with the highest rate observed among those under 20 years of age. There was high in vitro resistance to commonly used antibiotics such as ciprofloxacin and roxithromycin among the isolates. These findings provide local epidemiologic and antimicrobial susceptibility data for pregnant and postpartum women and highlight the need for further multi-center studies to confirm regional resistance patterns and clarify their clinical implications, including when genital mycoplasma colonization may warrant intervention.

Indexed as

Cervix UteriDrug Resistance, BacterialMycoplasma hominisMycoplasma InfectionsPregnancy Complications, InfectiousUreaplasmaUreaplasma InfectionsAdolescentAdultAnti-Bacterial AgentsChinaFemaleHumansMicrobial Sensitivity TestsPostpartum PeriodPregnancyAnti-Bacterial AgentsAntibiotic susceptibilityBacterial colonizationCiprofloxacin resistanceGenital mycoplasmasMacrolide resistanceMaternal healthMicrobial epidemiologyNeonatal outcomesPerinatal colonizationSexually Transmitted Infections (STIs)

Identifiers

PMID42332573
PMCPMC13440012

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LicenceCC BY-NC-ND
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