ArticleAnnals of hepato-biliary-pancreatic surgery2026
Effect of dual hepatic and portal vein embolization on future liver remnant function and volume prior to major hepatectomy.
Article in Annals of hepato-biliary-pancreatic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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15 authors.
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Abstract
Backgrounds/Aims: Dual hepatic and portal vein embolization, also known as dual venous embolization (DVE), is a potentially superior alternative to portal vein embolization for enhancing liver regeneration prior to major hepatectomy. This study evaluates the impact of DVE on the kinetic growth rate (KGR), volume increase (VI), functional increase (FI), and the correlation between volume and functional changes in the future liver remnant (FLR). Methods: Patients who underwent DVE with pre- and post-procedure volume and functional assessments were included. Growth rates of FLR volume and function were assessed using Tc99-mebrofenate single-photon emission computed tomography-computed tomography (Tc99-m SPECT-CT) scans. Correlation coefficients (R) were calculated to evaluate the relationship between VI and FI. Results: Among the 37 patients included, 27 proceeded to definitive surgery. The median time between DVE and the functional scan was 33 days (interquartile range [IQR], 13-69). The median increase in FLR volume was 30% (IQR, 14-50), and FLR function increased by 75% (IQR, 25-122) ( Conclusions: The increase in FLR function following DVE is significantly greater than the increase in volume. Earlier SPECT-CT scans may reduce delays to surgery and warrant further investigation.
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