Evidence map›Paper›PMID 42333705›Full record

ArticleJournal of the American Heart Association2026

Yihao Li, Florian Kronenberg, Stefan Coassin, Badri Vardarajan, Gissette Reyes-Soffer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yihao LiGertrude H. Sergievsky Center, Department of Neurology Columbia University Vagelos College of Physicians and Surgeons New York NY.ORCID 0009-0009-8722-3437
Florian KronenbergInstitute of Genetic Epidemiology Medical University of Innsbruck Innsbruck Austria.ORCID 0000-0003-2229-1120
Stefan CoassinInstitute of Genetic Epidemiology Medical University of Innsbruck Innsbruck Austria.ORCID 0000-0001-5677-8979
Badri VardarajanGertrude H. Sergievsky Center, Department of Neurology Columbia University Vagelos College of Physicians and Surgeons New York NY.ORCID 0000-0002-5560-4085
Gissette Reyes-SofferDivision of Preventive Medicine and Nutrition, Department of Medicine Columbia University Vagelos College of Physicians and Surgeons New York NY.ORCID 0000-0002-6746-4569

Funding

Unraveling the Complexity of Lipoprotein(a) Metabolism: Human Kinetic StudiesR01HL139759 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Gissette Reyes-Soffer · 2018 to 2026
$3.9M
NHLBI NIH HHS R01 HL139759
6 · The paper itself

Abstract

backgroundHigh plasma lipoprotein (a) (Lp[a]) levels, largely regulated by variation in the

methodsWhole-exome sequencing data from 3817 participants in the Washington Heights Inwood Columbia Aging Project were analyzed, including 886 non-Hispanic White individuals (23%), 1811 Caribbean Hispanic individuals (47%), and 1120 Black individuals (29%).

resultsA total of 1421 variants were identified in the

conclusionsNovel

Indexed as

Blood GlucoseHypertensionKringlesLipoprotein(a)AgedBlack or African AmericanExome SequencingFemaleGenetic Predisposition to DiseaseGenetic VariationHispanic or LatinoHumansMaleMiddle AgedPhenotypeRisk FactorsBlood GlucoseLipoprotein(a)LPA protein, humanancestry‐specific genetic variationatherosclerotic cardiovascular diseasehypertensionlipoprotein(a)LPA Kringle IV type 2 copy number

Identifiers

PMID42333705
PMCPMC13477386

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.