ArticleOphthalmology and therapy2026
Six-Month Real-World Data in Macular Edema Due to Retinal Vein Occlusion Treated with Faricimab: Swiss Retina Research Network Report.
Article in Ophthalmology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFaricimab has been shown to be effective for treatment of macular edema (ME) due to retinal vein occlusion (RVO). So far, there is only limited evidence in real-life settings and hard-to-treat cases.
methodsThis multicenter, retrospective study evaluated patients with branch or central (including hemi-central) RVO treated with a faricimab treat-and-extend regimen with at least 6 months of follow-up (FU). Data included best-corrected visual acuity (BCVA), center-point retinal thickness (CRT), central subfield thickness (CST), presence of intra- and subretinal fluid in the 1, 3, and 6 mm Early Treatment Diabetic Retinopathy Study (ETDRS) grid zones, number of injections, and adverse events at baseline and at 1, 3-4, and 6 months of faricimab therapy. Pretreated eyes were additionally evaluated at predefined time points of the pretreatment period.
resultsA total of 112 eyes from 111 patients, including 13 treatment-naive and 99 pretreated eyes, were included. BCVA improved in treatment-naïve eyes from 0.46 ± 0.28 logarithm of the minimum angle of resolution (logMAR) at baseline to 0.32 ± 0.28 logMAR 6 months later (p = 0.041). BCVA remained stable in pretreated eyes (0.20 ± 0.25 vs. 0.21 ± 0.29 logMAR; p = 0.7). CRT and CST improved in both groups: in treatment-naïve eyes, CRT from 522 to 267 µm (p < 0.001) and CST from 467 to 301 µm (p = 0.032); in pretreated eyes, CRT from 275 to 253 µm (p = 0.009) and CST from 315 to 293 µm (p = 0.001). Significant resolution in retinal fluid was shown in the central 1 mm (p ≤ 0.014), 3 mm (p ≤ 0.013), and 6 mm zones (p ≤ 0.013) of the ETDRS grid in both groups. Over 6 months, treatment-naïve and pretreated eyes received a mean of 5 ± 1 injections. One systemic adverse event and no intraocular inflammation were recorded during FU.
conclusionThis study demonstrates good real-world efficacy with significant drying and promising safety profile of faricimab in eyes with ME due to RVO, including a high proportion of hard-to-treat cases, over a 6-month period.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.