Evidence map›Paper›PMID 42334769›Full record

ArticleIrish journal of medical science2026

The association between composite dietary antioxidant index and the presence of cancer in elderly.

Yingying Xu, Wanwei Wang, Xiuying Sun, Tingting Hu

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Article in Irish journal of medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yingying Xu *Department of Radiation Oncology, The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, 223300, China.
Wanwei Wang *Department of Radiation Oncology, The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, 223300, China.
Xiuying SunDepartment of Otorhinostomology, The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, 223300, China. sunxiuy2107@163.com.
Tingting HuDepartment of Cardiology, The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, 223300, China. drhutt@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOxidative stress and antioxidant balance play critical roles in carcinogenesis, particularly among older adults who experience increased oxidative burden. This study explored the association between the composite dietary antioxidant index (CDAI) and cancer prevalence in the elderly.

methodsData from 4,907 elderly participants were analyzed and categorized into quartiles (Q1-Q4) according to CDAI. Logistic regression models estimated odds ratios (ORs) and 95% confidence intervals (CIs) for cancer across quartiles, adjusting for demographic and clinical covariates. Subgroup analyses were performed to evaluate the consistency across subgroups.

resultsParticipants with higher CDAI levels were more likely to be male, educated, and have lower diabetes prevalence. The prevalence of cancer increased across CDAI quartiles (19.6% in Q1 to 27.5% in Q4, P < 0.001). In fully adjusted models, Q4 had higher odds of cancer (OR = 1.26, 95% CI 1.02-1.54, P = 0.029). Subgroup analyses indicated stronger associations among women and those with diabetes.

conclusionsUnexpectedly, higher CDAI was associated with a greater prevalence of cancer among elderly individuals, suggesting complex, context-dependent effects of dietary antioxidants on cancer prevalence.

Indexed as

CancerComposite dietary antioxidant indexElderlyNutrition epidemiologyOxidative stress

Identifiers

PMID42334769

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.