Evidence map›Paper›PMID 42335240›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Fasting primes small intestinal regeneration after damage via a microbiome-metabolite-chromatin axis.

Praveen Barrodia, Ajay Kumar Saw, Sabrina L Jeter-Jones, Chia-Chi Chang, Jiansu Shao, Emre Arslan, Anand K Singh, Suresh Satpati, Robert R Jenq, Kunal Rai and 1 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Fasting primes small intestinal regeneration after damage via a microbiome-metabolite-chromatin axis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Praveen BarrodiaDepartment of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.ORCID 0000-0001-7932-2325
Ajay Kumar SawDepartment of Genomic Medicine and MDACC Epigenomics Therapy Initiative, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Sabrina L Jeter-JonesDepartment of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Chia-Chi ChangDepartment of Genomic Medicine and MDACC Epigenomics Therapy Initiative, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Jiansu ShaoDepartment of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Emre ArslanDepartment of Genomic Medicine and MDACC Epigenomics Therapy Initiative, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Anand K SinghDepartment of Genomic Medicine and MDACC Epigenomics Therapy Initiative, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Suresh SatpatiDepartment of Genomic Medicine and MDACC Epigenomics Therapy Initiative, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Robert R JenqDepartment of Genomic Medicine and MDACC Epigenomics Therapy Initiative, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Kunal RaiDepartment of Genomic Medicine and MDACC Epigenomics Therapy Initiative, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Helen Piwnica-WormsDepartment of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.ORCID 0000-0003-4210-6738

Funding

Mechanisms of fasting-induced radioprotection of small intestinal epithelial cellsR01CA269495 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HELEN M PIWNICA-WORMS, Kunal Rai · 2023 to 2026
$2.6M
Cancer Prevention and Research Institute of Texas (CPRIT) RP220567HHS | NIH | National Cancer Institute (NCI) R01CA269495
6 · The paper itself

Abstract

Fasting enhances small intestinal regeneration after radiation, but the contribution of the gut microbiome to this process remains uncharacterized. We identify

Indexed as

ChromatinFastingIntestine, SmallMicrobiotaRegenerationAnimalsEpigenesis, GeneticMiceMice, Inbred C57BLChromatinfastingmicrobiomeradiationregenerationstem cell

Identifiers

PMID42335240
PMCPMC13320697

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.