Evidence map›Paper›PMID 42335286›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2026

Nocturnal Intraocular Pressure Monitoring With a Soft Contact Lens Sensor for Glaucoma Management.

Yumin Dai, Tristan Michael Long, Oluwabunmi T Oladele, Youngoh Lee, Feiyang Li, Ziheng Wang, Yeonji Oh, Junsang Lee, Taewoong Park, Tianhao Yu and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Yumin DaiSchool of Materials Engineering, Purdue University, West Lafayette, IN, USA.
Tristan Michael LongSchool of Optometry, Indiana University, Bloomington, IN, USA.
Oluwabunmi T OladeleDepartment of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN, USA.
Youngoh LeeWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Feiyang LiWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Ziheng WangSchool of Mechanical Engineering, Purdue University, West Lafayette, IN, USA.
Yeonji OhWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Junsang LeeWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Taewoong ParkWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Tianhao YuSchool of Mechanical Engineering, Purdue University, West Lafayette, IN, USA.
Seokkyoon HongWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Kyeonghee LimSchool of Materials Engineering, Purdue University, West Lafayette, IN, USA.
Jinheon JeongWeldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Dawn Meyer SchneiderSchool of Optometry, Indiana University, Bloomington, IN, USA.
Hyerim RaDepartment of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN, USA.
Bryan W BoudourisCharles D. Davidson School of Chemical Engineering, Purdue University, West Lafayette, IN, USA.
Gillian C ShawSchool of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.
Shin Ae ParkDepartment of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN, USA.
Pete S KollbaumSchool of Optometry, Indiana University, Bloomington, IN, USA.
Chi Hwan LeeSchool of Materials Engineering, Purdue University, West Lafayette, IN, USA.ORCID https://orcid.org/0000-0002-4868-7054

Funding

Smart soft contact lenses for continuous 24-hour monitoring of intraocular pressure in glaucoma careR01EY034901 · PURDUE UNIVERSITY · 2025 to 2025
$511k
Korea Institute for Advancement of Technology P0028319Ministry of Trade, Industry, and Energy, KoreaNEI NIH HHS R01EY034901NIH HHS
6 · The paper itself

Abstract

Measurement of nocturnal intraocular pressure (IOP) is essential for glaucoma management, yet recumbent IOP fluctuations during sleep remain largely unmeasured outside the clinic. Although existing eye-worn wearable sensors enable noninvasive IOP monitoring, limitations in sensitivity, closed-eye performance, and overnight wearability restrict accurate assessment of nocturnal IOP changes under sleep conditions. Here, we present a soft contact lens sensor designed for continuous monitoring of nocturnal IOP in a home setting. The sensor integrates a compliant conductor-based inductive-capacitive circuit directly onto a commercial soft contact lens, enabling close conformity to the eye. This design achieves the highest IOP sensitivity reported to date among wearable soft contact lens sensors, representing a substantial improvement over our earlier designs. As a result, the sensor provides stable and accurate IOP measurements under recumbent, closed-eye sleep conditions. Animal studies in rabbits and dogs and pilot human measurements in healthy and glaucomatous eyes support preliminary ocular tolerability and feasible sensor performance, enabling posture-dependent IOP tracking and detection of sleep-relevant pressure elevations under the tested conditions. These results address key limitations of earlier contact lens sensors and support at-home monitoring of nocturnal IOP dynamics.

Indexed as

Contact Lenses, HydrophilicGlaucomaIntraocular PressureAnimalsDogsHumansMonitoring, PhysiologicRabbitsglaucoma managementintraocular pressure monitoringnocturnal monitoringsmart contact lenses

Identifiers

PMID42335286
PMCPMC13410647

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.