Evidence mapPaperPMID 42335316Full record

ReviewJournal of cardiovascular electrophysiology2026

Cardiac Implantable Electronic Devices in Oncology Patients: Challenges and Management.

Efstratios Karamanolis, Tereza López-Fernández, Maria Laura Canale, Gerasimos Filippatos, Dimitrios Farmakis

Abstract readReview
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In one paragraph

Review in Journal of cardiovascular electrophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Efstratios KaramanolisDepartment of Cardiology, Athens University Hospital Attikon, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Tereza López-FernándezDepartment of Cardiology, Cardio-Oncology Unit, La Paz University Hospital, Idi PAZ Research Institute, Madrid, Spain.
Maria Laura CanaleDepartment of Cardiology, Versilia Hospital, Azienda USL Toscana Nord-Ovest, Camaiore, Italia.ORCID https://orcid.org/0000-0003-0990-6397
Gerasimos FilippatosDepartment of Cardiology, Athens University Hospital Attikon, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.ORCID https://orcid.org/0000-0002-5640-0332
Dimitrios FarmakisDepartment of Cardiology, Athens University Hospital Attikon, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of cardiac implantable electronic devices (CIEDs) in patients with cancer is rising, given the increasing prevalence and incidence of cardiovascular disease in this population, such as arrhythmias and heart failure. Device therapy in oncology patients presents unique clinical, procedural, and ethical challenges, not completely addressed by current guidelines. This review summarizes current evidence regarding the indications, implantation challenges, long-term management, prognostic considerations and emerging technologies related to CIED therapy in oncology patients. Cancer-specific factors, such as thrombocytopenia, immunosuppression, prior surgery, and radiation-induced anatomical changes, complicate device implantation and follow-up. Increased infection risk, venous thromboembolism, and altered pacing thresholds, particularly in conditions like cardiac amyloidosis, require individualized approaches. The integration of leadless pacemakers, subcutaneous implantable cardioverter defibrillators (ICDs), wearable defibrillators, and remote monitoring offers promising alternatives for high-risk patients. Prognostic considerations and ethical dilemmas, including ICD implantation in patients with limited life expectancy and device deactivation at end-of-life, necessitate multidisciplinary decision-making. Future research and collaborative efforts are essential to address cancer-specific complexities and bridge existing gaps to optimize care for this growing patient population.

Indexed as

Arrhythmias, CardiacCardiac Pacing, ArtificialDefibrillators, ImplantableElectric CountershockNeoplasmsPacemaker, ArtificialHumansProsthesis DesignRisk AssessmentRisk FactorsTreatment Outcomecancercardiac implantable electronic devicescardiac resynchronization therapyimplantable cardioverter defibrillatoroncologypacemaker

Identifiers

PMID42335316

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.