ArticleJournal of clinical gastroenterology2026
A Quality Improvement Initiative to Increase Helicobacter pylori Testing and Eradication Among Patients Diagnosed With Peptic Ulcer Disease in a U.S. Safety-Net Hospital.
Article in Journal of clinical gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundHelicobacter pylori infection is the primary risk factor for peptic ulcer disease (PUD). Given rising antibiotic resistance, optimizing treatment and eradication remain paramount. We evaluated whether an educational intervention and an electronic medical record (EMR) bioinformatic intervention improved rates of H. pylori testing, treatment, and eradication testing in patients diagnosed with PUD in a safety-net hospital.
methodsWe examined potential gaps in H. pylori testing and treatment using a fishbone diagram and impact-effort matrix analyses. The first educational intervention consisted of multilingual educational templates for patients and providers on H. pylori testing and treatment. Second, we developed an EMR SmartSet order set to facilitate optimal antibiotic treatment and eradication testing. We determined rates of H. pylori testing, treatment, and eradication in preintervention (8/2020 to 2/2021), first postintervention (5/2021 to 3/2022), and second postintervention groups (7/2022 to 12/2022).
resultsAmong 351 patients with PUD, rates of H. pylori testing remained consistent across the preintervention, first postintervention, and second postintervention groups (mean 93.2%). Rates of optimal treatment (defined as bismuth-quadruple, clarithromycin-quadruple, or rifabutin-triple therapy with a proton pump inhibitor for 14 d) increased from 22.7% preintervention to 66.0% in the second postintervention group (P=0.001). Post-treatment eradication testing among infected patients increased from 49.7% to 60.3% in the second postintervention group (P=0.583), and confirmed H. pylori eradication improved from 59% to 63% in the second postintervention group (P=0.950).
conclusionsAn educational intervention and an EMR order set significantly increased rates of optimal, evidence-based treatment of H. pylori among PUD patients and modestly improved post-treatment eradication testing and confirmed eradication.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.