Evidence mapPaperPMID 42337178Full record

ReviewStem cell reviews and reports2026

Research Progress on Biomaterial Scaffolds Carrying Stem Cells for Inflammation Regulation After Spinal Cord Injury.

Nanjian Xu, Xiaoyin Chai, Weihu Ma, Weihu Zhang, Fang Yang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Stem cell reviews and reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nanjian XuSpine Surgery Center, Ningbo No.6 Hospital, 1059# Zhongshan East Road, Ningbo City, 315040, Zhejiang Province, PR China.
Xiaoyin ChaiDepartment of Nursing, Ningbo No.6 Hospital, 1059# Zhongshan East Road, Ningbo city, 315040, Zhejiang Province, China.
Weihu MaSpine Surgery Center, Ningbo No.6 Hospital, 1059# Zhongshan East Road, Ningbo City, 315040, Zhejiang Province, PR China.
Weihu ZhangDepartment of Nursing, Ningbo No.6 Hospital, 1059# Zhongshan East Road, Ningbo city, 315040, Zhejiang Province, China.
Fang YangDepartment of Nursing, Ningbo No.6 Hospital, 1059# Zhongshan East Road, Ningbo city, 315040, Zhejiang Province, China. 15967870408@163.com.

Funding

National Key Research and Development Program of China 2023YFC3604401Ningbo Clinical Research Center for Orthopedics, Sports Medicine & Rehabilitation 2024L004Ningbo Municipal Health Technology/Science and Technology Program Project 2025Y49
6 · The paper itself

Abstract

The inflammatory cascade triggered by spinal cord injury (SCI) presents a major barrier to tissue repair. This review summarizes recent advances in this field. It outlines the selection criteria for different scaffold materials and stem cells. It also describes key strategies for the coordinated regulation of the inflammatory microenvironment, including structural support and immunomodulation. In addition, the review discusses cell-free therapies and the functionalization of stem cell-derived materials. Intelligent responsive systems are also highlighted. Furthermore, this article evaluates the validation of these approaches in preclinical models. It also examines the challenges associated with their clinical translation. Finally, emerging trends, including dynamic adaptation, functional integration, and precise regeneration, are discussed. This review aims to provide a theoretical foundation and to guide future research on combination therapies for SCI.

Indexed as

Immune microenvironmentNerve regenerationSCISmart biomaterialsStem cell exosomesTissue engineering

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.