Evidence map›Paper›PMID 42337397›Full record

ArticleBMC plant biology2026

Characterizing the molecular mechanism of the PmIDD5-PmbHLH130-PmCOL5 transcriptional cascade on flowering in Prunus mume.

Chengdong Ma, Pengyu Zhou, Liping Tong, Silas Segbo, Ximeng Lin, Xiao Huang, Ting Shi, Zhaojun Ni, Zhihong Gao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Chengdong MaLaboratory of Fruit Tree Biotechnology, College of Horticulture, Nanjing Agricultural University, No.1 Weigang, Nanjing, Jiangsu, 210095, PR China.
Pengyu ZhouLaboratory of Fruit Tree Biotechnology, College of Horticulture, Nanjing Agricultural University, No.1 Weigang, Nanjing, Jiangsu, 210095, PR China.
Liping TongLaboratory of Fruit Tree Biotechnology, College of Horticulture, Nanjing Agricultural University, No.1 Weigang, Nanjing, Jiangsu, 210095, PR China.
Silas SegboLaboratory of Fruit Tree Biotechnology, College of Horticulture, Nanjing Agricultural University, No.1 Weigang, Nanjing, Jiangsu, 210095, PR China.
Ximeng LinLaboratory of Fruit Tree Biotechnology, College of Horticulture, Nanjing Agricultural University, No.1 Weigang, Nanjing, Jiangsu, 210095, PR China.
Xiao HuangLaboratory of Fruit Tree Biotechnology, College of Horticulture, Nanjing Agricultural University, No.1 Weigang, Nanjing, Jiangsu, 210095, PR China.
Ting ShiLaboratory of Fruit Tree Biotechnology, College of Horticulture, Nanjing Agricultural University, No.1 Weigang, Nanjing, Jiangsu, 210095, PR China.
Zhaojun NiLaboratory of Fruit Tree Biotechnology, College of Horticulture, Nanjing Agricultural University, No.1 Weigang, Nanjing, Jiangsu, 210095, PR China.
Zhihong GaoLaboratory of Fruit Tree Biotechnology, College of Horticulture, Nanjing Agricultural University, No.1 Weigang, Nanjing, Jiangsu, 210095, PR China. gaozhihong@njau.edu.cn.

Funding

"JBGS" Project of Seed Industry Revitalization in Jiangsu Province JBGS〔2021〕019National Natural Science Foundation of China 32372670Postgraduate Research and Practice Innovation Program of Jiangsu Province, China KYCX23_0798Priority Academic Program Development of Jiangsu Higher Education Institutions PAPD
6 · The paper itself

Abstract

backgroundPrunus mume is an important woody ornamental and fruit tree of Rosaceae. Elucidating the molecular regulatory network of its flowering is of great significance for genetic improvement. The basic helix-loop-helix (bHLH) and INDETERMINATE DOMAIN (IDD) transcription factors play vital roles in plant development processes, while their regulatory cascades in Prunus mume remain largely unclear.

resultsThis study reports a bHLH transcription factor PmbHLH130 in Prunus mume, whose transcription level responds to photoperiod, and which is predominantly expressed in leaves. Subcellular localization and transcriptional activity assays revealed that PmbHLH130 is a nuclear-localized transcriptional activator. Overexpressed PmbHLH130 significantly promotes flowering in transgenic Arabidopsis. PmbHLH130 acts downstream of several central oscillator proteins and PmIDD5, and directly activates the expression of PmCOL5.

conclusionThis study reveals that PmIDD5-PmbHLH130-PmCOL5 transcriptional cascade provides a molecular basis for understanding flowering regulation. These findings provide new insights into the molecular mechanisms of flowering control in woody plants and offer a potential framework for molecular breeding of Prunus mume.

Indexed as

Basic Helix-Loop-Helix ProteinsFlowersPlant ProteinsPrunusTranscription FactorsArabidopsisGene Expression Regulation, PlantPlants, Genetically ModifiedBasic Helix-Loop-Helix ProteinsPlant ProteinsTranscription FactorsFlowering timePmbHLH130Prunus mumeTranscriptional cascade

Identifiers

PMID42337397
PMCPMC13543614

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.