ArticleBMC anesthesiology2026
Feasibility of remimazolam rescue sedation for neonatal MRI: a case report.
Article in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
backgroundHigh-quality neonatal imaging often necessitates sedation or anesthesia to minimize motion artifacts. However, procedural sedation for non-painful pediatric examinations outside the operating room presents unique challenges due to their distinct cardiopulmonary physiology and drug metabolism. Although remimazolam is associated with minimal hemodynamic and respiratory effects in adults, evidence supporting its use in neonatal MRI remains limited. CASE DESCRIPTION: We report the first successful application of remimazolam for MRI sedation in an early-term neonate (37 ⁴⁄₇ weeks' gestational age, 2.9 kg). After unsuccessful non-pharmacologic measures and intranasal dexmedetomidine, intravenous remimazolam (0.1 mg/kg) produced adequate sedation within 1 min, allowing completion of a 17-minute MRI examination while preserving hemodynamic and respiratory stability.
conclusionsThis case highlights potential utility of remimazolam s a rescue sedative for neonatal MRI sedation. Comprehensive multicenter studies are warranted to evaluate its safety, efficacy, and role in clinical practice.
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