Evidence map›Paper›PMID 42337565›Full record

ArticleBMC psychiatry2026

Symptoms of depression, suicidal ideation, and personality traits in a sample of medical students: a cross-sectional study.

Stipe Vidović, Niko Morović, Ivanka Maduna, Marija Heffer, Dunja Degmečić, Marija Jelić Vuković, Slavica Kozina, Zenon Pogorelić

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Article in BMC psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Stipe VidovićFaculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, 31000, Croatia.
Niko MorovićSchool of Medicine Split, University of Split, Split, 21 000, Croatia.
Ivanka MadunaFaculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, 31000, Croatia.
Marija HefferFaculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, 31000, Croatia.
Dunja DegmečićDepartment of Psychiatry and Psychological Medicine, Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, 31000, Croatia.
Marija Jelić VukovićFaculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, 31000, Croatia.
Slavica KozinaDepartment of Medical Psychology, School of Medicine, University of Split, Split, 21000, Croatia.
Zenon PogorelićDepartment of Surgery, School of Medicine, University of Split, Spinčićeva ulica 1, Split, 21000, Croatia. zenon.pogorelic@mefst.hr.ORCID http://orcid.org/0000-0002-1517-720X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedical education is associated with substantial psychological demands, and accumulating evidence indicates a high prevalence of depressive symptoms and suicidal ideation among medical students, in some studies exceeding levels observed in non-medical student populations. However, data from Croatia remain limited, and the role of personality traits as potential vulnerability or protective factors remains insufficiently explored. This study aimed to assess the prevalence of depressive symptoms and suicidal ideation among medical students and to examine their associations with personality traits. We hypothesized that higher levels of depressive symptoms and suicidal ideation would be associated with lower levels of emotional stability, conscientiousness, and extraversion.

methodsThis cross-sectional study was conducted among medical students at the University of Split between 15 October and 15 November 2025. Depressive symptoms were assessed using the Patient Health Questionnaire-9 (PHQ-9). Personality traits (extraversion, agreeableness, conscientiousness, emotional stability, and intellect/imagination) were measured using the International Personality Item Pool-50 (IPIP-50).

resultsA total of 278 students were included (72.3% female; median age 22 years, IQR 20-24). At least mild depressive symptoms were reported by 61.2% of participants, while 9% exhibited moderately severe to severe symptoms. Suicidal ideation was reported by 12.2%. Female students reported higher depression scores compared with males (p < 0.001). Students with suicidal ideation showed significantly lower levels of extraversion (p < 0.001), conscientiousness (p < 0.001), and emotional stability (p < 0.001). Depression scores were negatively correlated with emotional stability (ρ = -0.468, p < 0.001), conscientiousness (ρ = -0.28, p < 0.001), agreeableness (ρ = -0.12, p < 0.05), and extraversion (ρ = -0.216, p < 0.001). In multivariable analysis, emotional stability (β = -1.088, p < 0.001), conscientiousness (β = -0.284, p = 0.007), and extraversion (β = -0.164, p = 0.047) emerged as the strongest independent correlates of depressive symptom severity.

conclusionDepressive symptoms and suicidal ideation were highly prevalent among medical students. Depressive symptom severity was negatively associated with several personality traits, particularly emotional stability, conscientiousness, and extraversion, which emerged as the strongest correlates. These findings highlight the relevance of personality traits in understanding depressive symptoms among student population and support the need for further longitudinal research and mental health prevention strategies.

Indexed as

DepressionPersonalityStudents, MedicalSuicidal IdeationAdultCroatiaCross-Sectional StudiesFemaleHumansMalePrevalenceYoung AdultDepressionMedical studentsMental disordersMental healthPersonality traitsStudentsSuicidal ideation

Identifiers

PMID42337565
PMCPMC13551946

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.