Evidence map›Paper›PMID 42337682›Full record

ArticleBiomarker research2026

INHBA-S100A16 dysregulation enables a non-invasive molecular stratification platform for rapid detection of oral squamous cell carcinoma: results from a large diagnostic case-control study.

Muy-Teck Teh, Ranjitkumar Patil, Satyajit Ashok Tekade, Deepika Mishra, Akhilanand Chaurasia, Ahmad Waseem

Abstract read
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In one paragraph

Article in Biomarker research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Muy-Teck TehCentre for Oral Immunobiology & Regenerative Medicine, Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, The Blizard Building, 4, Newark Street, London, E1 2AT, UK. m.t.teh@qmul.ac.uk.ORCID http://orcid.org/0000-0002-7725-8355
Ranjitkumar PatilDepartment of Oral Medicine & Radiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Satyajit Ashok TekadeDepartment of Oral & Maxillofacial Pathology, Modern Dental College & Research Centre, Indore, Madhya Pradesh, India.
Deepika MishraDepartment of Oral Pathology & Microbiology, Centre of Dental Education & Research, All India Institute of Medical Sciences, New Delhi, India.
Akhilanand ChaurasiaDepartment of Oral Medicine & Radiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Ahmad WaseemCentre for Oral Immunobiology & Regenerative Medicine, Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, The Blizard Building, 4, Newark Street, London, E1 2AT, UK.

Funding

Barts Centre for Squamous Cancer funded by Barts Charity G-002030
6 · The paper itself

Abstract

backgroundEarly diagnosis of oral squamous cell carcinoma (OSCC) is critical, yet most oral potentially malignant disorders (OPMDs) are benign, and patients frequently undergo unnecessary invasive scalpel biopsies, creating diagnostic delays and patient harm. A rapid, non-invasive molecular diagnostic tool could improve early detection and reduce unnecessary procedures. This study aims to determine whether a previously validated microbiopsy-based multigene assay (qMIDS

methodsThis prospective diagnostic case-control study validated a multigene mRNA test (qMIDS

resultsqMIDS

conclusionsOur findings highlight the clinical utility of qMIDS

Indexed as

Brush biopsyEarly detectionEarly oral cancer biomarkersHead and neck cancerINHBAmRNANon-invasiveOral cancerOral cancer screeningPOLR2AqMIDSRT-qPCRS100A16Squamous cell carcinomaYAP1

Identifiers

PMID42337682
PMCPMC13335036

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.