Evidence map›Paper›PMID 42338009›Full record

ArticleMicrobiologyOpen2026

Effect of Increased Inoculum Size on Drug Susceptibility of Mycobacterium tuberculosis: Challenges in Reliable Drug Resistance Detection.

Kubra Yildirim, Cemilenur Atas, Ece Simsek, Mir Pooya Salehi Moharer, Meltem Uzun, Ahmet Yilmaz Coban

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MicrobiologyOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kubra YildirimFaculty of Health Sciences Research Laboratory, Tuberculosis Research Unit, Akdeniz University, Antalya, Turkey.
Cemilenur AtasFaculty of Health Sciences Research Laboratory, Tuberculosis Research Unit, Akdeniz University, Antalya, Turkey.
Ece SimsekFaculty of Health Sciences Research Laboratory, Tuberculosis Research Unit, Akdeniz University, Antalya, Turkey.
Mir Pooya Salehi MoharerPrivate Akdeniz Sifa Hospital, Antalya, Turkey.
Meltem UzunDepartment of Medical Microbiology, Istanbul Medical School, Istanbul University, Capa, Istanbul, Turkey.
Ahmet Yilmaz CobanFaculty of Health Sciences Research Laboratory, Tuberculosis Research Unit, Akdeniz University, Antalya, Turkey.ORCID 0000-0002-8815-6063

Funding

Scientific Research Projects Coordination Unit of Akdeniz University TSA-2022-6124
6 · The paper itself

Abstract

Inoculum preparation of Mycobacterium tuberculosis isolates is a critical step for the reproducibility of drug susceptibility tests (DST) and the prevention of false results. In this study, we investigated the effect of increasing inoculum sizes of M. tuberculosis isolates on DST. For this purpose, primary drug susceptibilities of five ATCC strains and 24 M. tuberculosis isolates were determined by the proportion method on 7H10 agar using six different inoculum sizes (10

Indexed as

Antitubercular AgentsDrug Resistance, BacterialMycobacterium tuberculosisHumansMicrobial Sensitivity TestsReproducibility of ResultsStreptomycinAntitubercular AgentsStreptomycindrug susceptibility testinoculum densityinoculum sizeMycobacterial inoculumMycobacterium tuberculosistuberculosis

Identifiers

PMID42338009
PMCPMC13291193

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.