Evidence map›Paper›PMID 42338698›Full record

ReviewCardiology research and practice2026

Bibliometric Analysis of Research Hotspots and Emerging Trends in Mitochondrial DNA and Atherosclerosis (2004-2025).

Yun Ouyang, Gesheng Wang, Ming Zhang, Puxuan Min, Mengxiong Guo

Abstract readReview
In one paragraph

Review in Cardiology research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yun OuyangGraduate School, Beijing University of Chinese Medicine, Beijing, China, bucm.edu.cn.ORCID https://orcid.org/0009-0002-9368-8096
Gesheng WangDepartment of Neurology III, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China, bucm.edu.cn.ORCID https://orcid.org/0000-0002-8724-3392
Ming ZhangGraduate School, Beijing University of Chinese Medicine, Beijing, China, bucm.edu.cn.ORCID https://orcid.org/0000-0003-4656-1324
Puxuan MinGraduate School, Beijing University of Chinese Medicine, Beijing, China, bucm.edu.cn.ORCID https://orcid.org/0009-0002-8048-8001
Mengxiong GuoGraduate School, Beijing University of Chinese Medicine, Beijing, China, bucm.edu.cn.ORCID https://orcid.org/0009-0009-9158-8359

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the research course, hotspots, and development trends of mitochondrial DNA (mtDNA) and atherosclerosis (AS) based on knowledge graph technology, providing references for clinical and basic research in this field. Methods: Publications themed on mtDNA and AS published between 2004 and 2025 were retrieved from the Web of Science Core Collection (WOSCC) database. CiteSpace 6.4. R1 Advanced software was used to construct and visually analyze knowledge graphs of authors, institutions, keywords, etc. Results: A total of 341 publications were included, with the annual publication volume showing an overall upward trend. Research methods for mtDNA and AS are diversifying, with mechanistic investigations showing a trending focus toward specific molecular pathways. A total of 241 authors and 353 publishing institutions were analyzed. Ten keyword clusters were identified, including Cluster #0 oxidative stress, Cluster #1 mitochondrial DNA, Cluster #2 degradation, Cluster #3 atherosclerosis, Cluster #4 hydrogen peroxide, Cluster #5 roles, Cluster #6 MAPK pathway, Cluster #7 epigallocatechin gallate, Cluster #8 mitochondrial DNA copy number, and Cluster #9 vascular disease. Conclusion: Research has evolved from foundational mechanistic studies to a focus on translational and clinical applications. Moving forward, efforts should be intensified to enhance collaboration among research teams and deepen mechanistic investigations, thereby laying a solid foundation for clinical translation.

Indexed as

atherosclerosis1bibliometrics5CiteSpace4mitochondrial DNA2oxidative stress3

Identifiers

PMID42338698
PMCPMC13284486

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.