Evidence map›Paper›PMID 42339178›Full record

ArticleToxicology reports2026

Effects of dinotefuran and its metabolites on the early life stage development of medaka (

Masashi Hirano, Daishi Inoue, Masaya Uchida, Keisuke Takahashi, Keisuke Kato, Tadashi Okobira, Hiroshi Ishibashi, Koji Arizono, Nobuaki Tominaga

Abstract read
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In one paragraph

Article in Toxicology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Masashi HiranoDepartment of Food and Life Sciences, School of Agriculture, Tokai University, 871-12 Sugido, Mashiki-Machi, Kamimashiki-Gun, Kumamoto 861-2205, Japan.
Daishi InoueDepartment of Creative Engineering, National Institute of Technology, Ariake College, 150 Higashi-Hagio, Omuta, Fukuoka 836-8585, Japan.
Masaya UchidaDepartment of Creative Engineering, National Institute of Technology, Ariake College, 150 Higashi-Hagio, Omuta, Fukuoka 836-8585, Japan.
Keisuke TakahashiFaculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan.
Keisuke KatoFaculty of Pharmaceutical Sciences, Toho University, 2-2-1 Miyama, Funabashi, Chiba 274-8510, Japan.
Tadashi OkobiraDepartment of Creative Engineering, National Institute of Technology, Ariake College, 150 Higashi-Hagio, Omuta, Fukuoka 836-8585, Japan.
Hiroshi IshibashiGraduate School of Agriculture, Ehime University, 3-5-7 Tarumi, Matsuyama, Ehime 790-8566, Japan.
Koji ArizonoGraduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe, Chuo-ku, Kumamoto, Kumamoto 862-0973, Japan.
Nobuaki TominagaDepartment of Creative Engineering, National Institute of Technology, Ariake College, 150 Higashi-Hagio, Omuta, Fukuoka 836-8585, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dinotefuran (DINO), a widely used neonicotinoid insecticide, has attracted significant attention because of its environmental risks. Although DINO is metabolized in the environment, its specific toxicological risks remain unclear. In this study, we aimed to determine the effects of DINO and its metabolites, 2-nitro-1-(tetrahydro-3-furylmethyl)guanidine (FNG), 1-methyl-3-(tetrahydro-3-furylmethyl) guanidine (DN), 1-methyl-3-(tetrahydro-3-furylmethyl)-urea (UF), and N-aminodinotefuran (NAD) on the embryonic development of medaka (

Indexed as

Developmental toxicityDinotefuran and its metabolitesMolecular dockingNeonicotinoid insecticidesOryzias latipes

Identifiers

PMID42339178
PMCPMC13284504

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.