ArticleEClinicalMedicine2026
Self-administered acupressure training for depression in community-dwelling individuals: a randomized controlled trial and cost-effectiveness analysis.
Article in EClinicalMedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05631184 (Self-administered Acupressure for Depression), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Self-administered Acupressure for Depression: A Randomized Controlled Trial
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Depression is a detrimental mental disorder. Self-administered acupressure (SAA), a flexible self-help intervention, may be beneficial for relieving depression. Methods: A randomized controlled trial with cost-effectiveness analysis was conducted in a community setting in Hong Kong, China, between November 20, 2022, and August 19, 2024. Adults with moderate depression were randomized into SAA or mental health education (MHE) group. Participants in the SAA group underwent an acupressure training program (two 2-h sessions); they were told to practice SAA daily for 12 weeks. Participants in the MHE group received mental health education with the same schedule and duration. The primary outcome was the Patient Health Questionnaire-9 (PHQ-9) score over 12 weeks. This study was registered in ClinicalTrials.gov (#NCT05631184). Findings: A total of 250 participants (186 female [74.4%]; mean [SD] age, 41.86 [12.85] years; mean [SD] depression duration, 5.58 [6.86] years) were recruited. The SAA group (n = 125) showed a significantly greater reduction from baseline in the PHQ-9 score than the MHE group across all assessment time points (week 4: mean difference -1.04 [95% CI: -2.02 to -0.06], Interpretation: Despite the clinically small effect sizes, the SAA training program is a potentially effective intervention for moderate depression. Funding: Health Medical Research Fund.
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