ArticleOphthalmology science2026
Sleep Pattern and Structural Damage in Older Adults with Glaucoma: A United States and China Study.
Article in Ophthalmology science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
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Abstract
Purpose: To investigate sleep patterns in older adults with glaucoma and evaluate their associations with glaucomatous damage and emotional disturbances. Design: A cross-sectional observational study. Participants: Adults aged ≥60 years from the National Health and Nutrition Examination Survey (NHANES) 2005-2008 in the United States (n = 3317) and the Elderly Glaucoma and Sleep Study (EGSS) in China (n = 200). Methods: Participants in NHANES and EGSS completed standardized sleep questionnaires and underwent ophthalmic examinations, while wearable derived-sleep measures and urinary melatonin metabolite assays were additionally performed in the EGSS cohort. In EGSS, multivariable linear regression models were used to examine associations of the Pittsburgh Sleep Quality Index (PSQI) global score with demographic, clinical, and ocular factors. Main Outcome Measures: Overall sleep disorder in NHANES and PSQI global score in EGSS. Results: In NHANES, older adults with glaucoma reported more frequent sleep disturbances than controls, showing higher odds of sleep disorders and difficulty initiating sleep, as well as longer sleep latency (all Conclusions: Older adults with glaucoma had poorer sleep quality. Participants with POAG showed poorer subjective sleep quality, a longer wearable-derived light sleep duration, and lower urinary melatonin metabolite levels. In POAG, poorer sleep quality was significantly associated with more severe glaucomatous structural damage and a greater depressive symptom burden. Financial Disclosures: The authors have no proprietary or commercial interest in any materials discussed in this article.
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