ArticleOphthalmology science2026
Pathways to Patchy Atrophy in High Myopia: Precursor Patterns, Structural Characteristics, and Long-Term Outcomes.
Article in Ophthalmology science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Intravitreal Dexamethasone Implant in Punctate Inner Choroidopathy: Clinical Indications and Outcomes in a Real-World Case Series.Ophthalmology and therapy · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To characterize distinct precursor patterns associated with the development of patchy atrophy (PA) in highly myopic eyes and to describe their structural evolution and clinical outcomes over time. Design: A retrospective multicenter cohort study. Participants: Highly myopic patients with documented onset of PAs and at least 3 months of multimodal imaging (MMI) prior to the PA development. Methods: Clinical, demographic, and MMI findings were retrospectively collected from 3 tertiary referral centers. Based on MMI findings preceding PA onset, eyes were categorized into 3 patterns: (1) inflammatory PAs in the context of punctate inner choroidopathy; (2) neovascular PAs, associated with extrafoveal macular neovascularization (MNV); and (3) idiopathic PAs, in the absence of identifiable inflammatory or neovascular precursor lesions. Main Outcome Measures: Precursor patterns, clinical and MMI characteristics, clinical complication profile, and atrophy growth rate (AGR). Results: The study included 103 eyes (84 patients; 28 [27%] men) with a mean (standard deviation) age of 62 (13.4) years and mean refractive error of -13.2 (5.8) diopters at PA onset. Median observation periods prior to PA onset and post-PA follow-up were 2.1 years (interquartile range 5.20) and 3.44 years (interquartile range 7.23), respectively. Inflammatory PAs were detected in 33 (32%) eyes, neovascular PAs in 9 (9%) eyes, and 61 eyes (59%) had idiopathic PAs. Number of pre-existing PAs at baseline was the highest in inflammatory PAs (6.1 ± 6.4), followed by neovascular PAs (1.6 ± 1.1) and idiopathic PAs (1.5 ± 1.1; Conclusions: Patchy atrophies in highly myopic eyes develop with 3 precursor patterns (inflammatory, neovascular, and idiopathic) and differ in structural characteristics, atrophy progression, and complication profile. Recognition of PA patterns may improve clinical assessment of highly myopic eyes. Financial Disclosures: The authors have no proprietary or commercial interest in any materials discussed in this article.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.