Evidence map›Paper›PMID 42339735›Full record

ArticleZoological research2026

Lethal VSV-based surrogate mouse models for Sudan and Bundibugyo ebolaviruses enable antibody evaluation under BSL-2 conditions.

Bao-Yue Zhang, Fang-Xu Li, Shen Wang, Jun-Hui Zhou, Jin-Ge Zhou, Yan Wu, Ying Xie, Wu-Jian Li, Fei-Hu Yan, Xing-Hai Zhang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zoological research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bao-Yue ZhangState Key Laboratory of Virology and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei 430062, China.
Fang-Xu LiState Key Laboratory of Virology and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei 430062, China.
Shen WangKey Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, Jinlin 130122, China.
Jun-Hui ZhouState Key Laboratory of Virology and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei 430062, China.
Jin-Ge ZhouState Key Laboratory of Virology and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei 430062, China.
Yan WuState Key Laboratory of Virology and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei 430062, China.
Ying XieHebei Key Lab of Laboratory Animal Science, Department of Laboratory Animal Science, Hebei Medical University, Shijiazhuang, Hebei 050017, China.
Wu-Jian LiDepartment of Infectious Disease, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230027, China.
Fei-Hu YanKey Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, Jinlin 130122, China. E-mail: yanfh1990@163.com.
Xing-Hai ZhangState Key Laboratory of Virology and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei 430062, China. E-mail: zhangxh@wh.iov.cn.
Sandra ChiuDepartment of Infectious Disease, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230027, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sudan (SUDV) and Bundibugyo (BDBV) ebolaviruses are major outbreak pathogens lacking approved vaccines or therapeutics. Research progress has been hampered by biosafety level 4 (BSL-4) restrictions. Here, we generated recombinant vesicular stomatitis viruses expressing SUDV or BDBV glycoproteins (VSV∆G-SUDV GP, VSV∆G-BDBV GP) and established lethal infection models in Type I interferon receptor knockout (IFNAR

Indexed as

Antibodies, ViralEbolavirusHemorrhagic Fever, EbolaVesicular stomatitis Indiana virusAnimalsAntibodies, MonoclonalDisease Models, AnimalMiceMice, KnockoutReceptor, Interferon alpha-betaViral LoadAntibodies, MonoclonalAntibodies, ViralReceptor, Interferon alpha-betaAnimal modelBundibugyo virus (BDBV)IFNAR-/- mouse modelSudan virus (SUDV)VSV-based surrogate virus

Identifiers

PMID42339735
PMCPMC13647154

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.