Evidence map›Paper›PMID 42342340›Full record

ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2026

Relationship between Vascular Tortuosity Rate and Atherosclerotic Risk Factors in Patients with Carotid Artery Stenosis.

Masanori Tsuji, Fujimaro Ishida, Yoichi Miura, Takenori Sato, Yume Suzuki, Hideki Kanamaru, Kazuhiro Furukawa, Takeshi Okada, Keiji Fukazawa, Ryuta Yasuda and 3 more

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Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Masanori TsujiDepartment of Neurosurgery, Mie University Graduate School of Medicine, Tsu Mie, Japan.
Fujimaro IshidaDepartment of Neurosurgery, Mie Chuo Medical Center, National Hospital Organization, Tsu Mie, Japan.
Yoichi MiuraDepartment of Neurosurgery, Kuwana City Medical Center, Kuwana Mie, Japan.
Takenori SatoDepartment of Neurosurgery, Japanese Red Cross Ise Hospital, Ise Mie, Japan.
Yume SuzukiDepartment of Neurosurgery, Mie University Graduate School of Medicine, Tsu Mie, Japan.
Hideki KanamaruDepartment of Neurosurgery, Mie University Graduate School of Medicine, Tsu Mie, Japan.
Kazuhiro FurukawaDepartment of Neurosurgery, Mie Chuo Medical Center, National Hospital Organization, Tsu Mie, Japan.
Takeshi OkadaDepartment of Neurosurgery, Mie University Graduate School of Medicine, Tsu Mie, Japan.
Keiji FukazawaDepartment of Neurosurgery, Mie Chuo Medical Center, National Hospital Organization, Tsu Mie, Japan.
Ryuta YasudaDepartment of Neurosurgery, Mie University Graduate School of Medicine, Tsu Mie, Japan.
Yasuyuki UmedaDepartment of Neurosurgery, Kuwana City Medical Center, Kuwana Mie, Japan.
Naoki TomaDepartment of Neurosurgery, Mie University Graduate School of Medicine, Tsu Mie, Japan.
Hidenori SuzukiDepartment of Neurosurgery, Mie University Graduate School of Medicine, Tsu Mie, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is a significant association between carotid artery (CA) stenosis and atherosclerosis, with those patients often presenting with carotid tortuosity. However, the relationship between atherosclerotic risk factors and carotid tortuosity remains controversial. Previous assessments of tortuosity have predominantly utilized qualitative 2D methods. This retrospective study aimed to quantitatively evaluate the tortuosity of CAs in 3D geometry and to investigate the relationship with atherosclerotic risk factors.

methodsA total of 168 CAs in 96 patients diagnosed with at least either-side CA stenosis on magnetic resonance angiography (MRA) between 2011 and 2019 were included in this single-center study, following the exclusion of post-treatment CAs and those with poor imaging quality. The 3D geometries of CAs were segmented using MRA and the centerlines were generated. Vascular tortuosity rate (VTR) was calculated as the curved distance divided by the linear distance between the specified 2 points. The relationship between VTRs and 8 atherosclerotic risk factors-age, body mass index, systolic blood pressure, hemoglobin A1c, high-density lipoprotein, total cholesterol (TC), non-fasting serum triglyceride (TG), and Brinkman index-was analyzed.

resultsHigher VTRs were associated with ≥65 years of age, body mass index ≥25 [kg/m

conclusionQuantitative assessment of carotid tortuosity revealed significant associations with several atherosclerotic risk factors, including obesity, hypertension, advanced age, and dyslipidemia, suggesting that VTRs may reflect the presence of these risk factors.

Indexed as

AtherosclerosisCarotid ArteriesCarotid StenosisMagnetic Resonance AngiographyAgedAged, 80 and overFemaleHumansImaging, Three-DimensionalMaleMiddle AgedRetrospective StudiesRisk Factorsatherosclerosiscarotid artery stenosisvascular tortuosity rate

Identifiers

PMID42342340
PMCPMC13549769

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.