In one paragraphArticle in Cellular & molecular immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Luisa BachMedical Clinic III for Oncology, Hematology, Immuno-Oncology and Rheumatology, University Hospital Bonn, University of Bonn, Bonn, Germany.ORCID 0000-0002-3476-6325 Yinshui ChangMedical Clinic III for Oncology, Hematology, Immuno-Oncology and Rheumatology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Olin Arteaga TransitoMedical Clinic III for Oncology, Hematology, Immuno-Oncology and Rheumatology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Mohammadamin GhasemiInstitute of Experimental Oncology, Biomathematics Division, University Hospital Bonn, University of Bonn, Bonn, Germany.
Lisa Maria SteinheuerInstitute of Experimental Oncology, Biomathematics Division, University Hospital Bonn, University of Bonn, Bonn, Germany.
Teresa SteffenMedical Clinic III for Oncology, Hematology, Immuno-Oncology and Rheumatology, University Hospital Bonn, University of Bonn, Bonn, Germany.ORCID 0009-0009-3311-5051 Elena De DomenicoPlatform for Single-Cell Genomics and Epigenomics at the University of Bonn and the German Center for Neurodegenerative Diseases and West German Genome Center, Bonn, Germany.ORCID 0000-0003-0336-8284 Thomas UlasPlatform for Single-Cell Genomics and Epigenomics at the University of Bonn and the German Center for Neurodegenerative Diseases and West German Genome Center, Bonn, Germany.
F Thomas WunderlichMax Planck Institute for Metabolism Research, Center for Endocrinology, Diabetes and Preventive Medicine (CEDP), Center for Molecular Medicine Cologne (CMMC), Cologne, Germany.ORCID 0000-0002-9209-3501 Marc D BeyerPlatform for Single-Cell Genomics and Epigenomics at the University of Bonn and the German Center for Neurodegenerative Diseases and West German Genome Center, Bonn, Germany.ORCID 0000-0001-9704-148X Kevin ThurleyInstitute of Experimental Oncology, Biomathematics Division, University Hospital Bonn, University of Bonn, Bonn, Germany.
Dirk BaumjohannMedical Clinic III for Oncology, Hematology, Immuno-Oncology and Rheumatology, University Hospital Bonn, University of Bonn, Bonn, Germany. dirk.baumjohann@uni-bonn.de.ORCID 0000-0001-8385-8288 Funding
Deutsche Forschungsgemeinschaft (German Research Foundation) 252623821Deutsche Forschungsgemeinschaft (German Research Foundation) 272482170Deutsche Forschungsgemeinschaft (German Research Foundation) 390685813Deutsche Forschungsgemeinschaft (German Research Foundation) 390873048Deutsche Forschungsgemeinschaft (German Research Foundation) 432325352
6 · The paper itselfAbstract
T follicular helper (Tfh) cells and T follicular regulatory (Tfr) cells play critical roles in regulating the activity of the germinal center (GC), which is essential for the generation of high-affinity antibodies. In the GC, Tfh cells help B cells to proliferate and to differentiate into memory B cells and long-lived plasma cells. In contrast, Tfr cells, a specialized subset of regulatory T cells (Tregs), modulate the humoral immune response by suppressing excessive or autoreactive B-cell activity. Here, we established an in vitro differentiation protocol for mouse CD4⁺ T cells that yielded CXCR5⁺FoxP3⁺ Tfr cells that exhibited a Bcl6
Indexed as
Cell DifferentiationInterleukin-2T-Lymphocytes, RegulatoryTransforming Growth Factor betaAnimalsB-LymphocytesForkhead Transcription FactorsGerminal CenterImmunoglobulin Class SwitchingImmunoglobulin GLymphocyte ActivationMiceMice, Inbred C57BLProto-Oncogene Proteins c-bcl-6Proto-Oncogene Proteins c-mafReceptors, CXCR5Bcl6 protein, mouseForkhead Transcription FactorsImmunoglobulin GInterleukin-2Proto-Oncogene Proteins c-bcl-6Proto-Oncogene Proteins c-mafReceptors, CXCR5Transforming Growth Factor betac-MafCXCR5FoxP3IL-2T follicular regulatory cells
Identifiers
PMID42342921
PMCPMC13424134
What Socratic holds
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